Abstract:Brain decoding, which aims at reconstructing visual stimuli from brain signals, primarily utilizing functional magnetic resonance imaging (fMRI), has recently made positive progress. However, it is impeded by significant challenges such as the difficulty of acquiring fMRI-image pairs and the variability of individuals, etc. Most methods have to adopt the per-subject-per-model paradigm, greatly limiting their applications. To alleviate this problem, we introduce a new and meaningful task, few-shot brain decoding, while it will face two inherent difficulties: 1) the scarcity of fMRI-image pairs and the noisy signals can easily lead to overfitting; 2) the inadequate guidance complicates the training of a robust encoder. Therefore, a novel framework named MindShot, is proposed to achieve effective few-shot brain decoding by leveraging cross-subject prior knowledge. Firstly, inspired by the hemodynamic response function (HRF), the HRF adapter is applied to eliminate unexplainable cognitive differences between subjects with small trainable parameters. Secondly, a Fourier-based cross-subject supervision method is presented to extract additional high-level and low-level biological guidance information from signals of other subjects. Under the MindShot, new subjects and pretrained individuals only need to view images of the same semantic class, significantly expanding the model's applicability. Experimental results demonstrate MindShot's ability of reconstructing semantically faithful images in few-shot scenarios and outperforms methods based on the per-subject-per-model paradigm. The promising results of the proposed method not only validate the feasibility of few-shot brain decoding but also provide the possibility for the learning of large models under the condition of reducing data dependence.
Abstract:Since signet ring cells (SRCs) are associated with high peripheral metastasis rate and dismal survival, they play an important role in determining surgical approaches and prognosis, while they are easily missed by even experienced pathologists. Although automatic diagnosis SRCs based on deep learning has received increasing attention to assist pathologists in improving the diagnostic efficiency and accuracy, the existing works have not been systematically overviewed, which hindered the evaluation of the gap between algorithms and clinical applications. In this paper, we provide a survey on SRC analysis driven by deep learning from 2008 to August 2023. Specifically, the biological characteristics of SRCs and the challenges of automatic identification are systemically summarized. Then, the representative algorithms are analyzed and compared via dividing them into classification, detection, and segmentation. Finally, for comprehensive consideration to the performance of existing methods and the requirements for clinical assistance, we discuss the open issues and future trends of SRC analysis. The retrospect research will help researchers in the related fields, particularly for who without medical science background not only to clearly find the outline of SRC analysis, but also gain the prospect of intelligent diagnosis, resulting in accelerating the practice and application of intelligent algorithms.
Abstract:Prototype-based classification is a classical method in machine learning, and recently it has achieved remarkable success in semi-supervised semantic segmentation. However, the current approach isolates the prototype initialization process from the main training framework, which appears to be unnecessary. Furthermore, while the direct use of K-Means algorithm for prototype generation has considered rich intra-class variance, it may not be the optimal solution for the classification task. To tackle these problems, we propose a novel boundary-refined prototype generation (BRPG) method, which is incorporated into the whole training framework. Specifically, our approach samples and clusters high- and low-confidence features separately based on a confidence threshold, aiming to generate prototypes closer to the class boundaries. Moreover, an adaptive prototype optimization strategy is introduced to make prototype augmentation for categories with scattered feature distributions. Extensive experiments on the PASCAL VOC 2012 and Cityscapes datasets demonstrate the superiority and scalability of the proposed method, outperforming the current state-of-the-art approaches. The code is available at xxxxxxxxxxxxxx.