EAP4EMSIG -- Experiment Automation Pipeline for Event-Driven Microscopy to Smart Microfluidic Single-Cells Analysis

Microfluidic Live-Cell Imaging (MLCI) generates high-quality data that allows biotechnologists to study cellular growth dynamics in detail. However, obtaining these continuous data over extended periods is challenging, particularly in achieving accurate and consistent real-time event classification at the intersection of imaging and stochastic biology. To address this issue, we introduce the Experiment Automation Pipeline for Event-Driven Microscopy to Smart Microfluidic Single-Cells Analysis (EAP4EMSIG). In particular, we present initial zero-shot results from the real-time segmentation module of our approach. Our findings indicate that among four State-Of-The- Art (SOTA) segmentation methods evaluated, Omnipose delivers the highest Panoptic Quality (PQ) score of 0.9336, while Contour Proposal Network (CPN) achieves the fastest inference time of 185 ms with the second-highest PQ score of 0.8575. Furthermore, we observed that the vision foundation model Segment Anything is unsuitable for this particular use case.

Transformer Training Strategies for Forecasting Multiple Load Time Series

Recent work uses Transformers for load forecasting, which are the state of the art for sequence modeling tasks in data-rich domains. In the smart grid of the future, accurate load forecasts must be provided on the level of individual clients of an energy supplier. While the total amount of electrical load data available to an energy supplier will increase with the ongoing smart meter rollout, the amount of data per client will always be limited. We test whether the Transformer benefits from a transfer learning strategy, where a global model is trained on the load time series data from multiple clients. We find that the global model is superior to two other training strategies commonly used in related work: multivariate models and local models. A comparison to linear models and multi-layer perceptrons shows that Transformers are effective for electrical load forecasting when they are trained with the right strategy.

Towards Automatic Parsing of Structured Visual Content through the Use of Synthetic Data

Structured Visual Content (SVC) such as graphs, flow charts, or the like are used by authors to illustrate various concepts. While such depictions allow the average reader to better understand the contents, images containing SVCs are typically not machine-readable. This, in turn, not only hinders automated knowledge aggregation, but also the perception of displayed in-formation for visually impaired people. In this work, we propose a synthetic dataset, containing SVCs in the form of images as well as ground truths. We show the usage of this dataset by an application that automatically extracts a graph representation from an SVC image. This is done by training a model via common supervised learning methods. As there currently exist no large-scale public datasets for the detailed analysis of SVC, we propose the Synthetic SVC (SSVC) dataset comprising 12,000 images with respective bounding box annotations and detailed graph representations. Our dataset enables the development of strong models for the interpretation of SVCs while skipping the time-consuming dense data annotation. We evaluate our model on both synthetic and manually annotated data and show the transferability of synthetic to real via various metrics, given the presented application. Here, we evaluate that this proof of concept is possible to some extend and lay down a solid baseline for this task. We discuss the limitations of our approach for further improvements. Our utilized metrics can be used as a tool for future comparisons in this domain. To enable further research on this task, the dataset is publicly available at https://bit.ly/3jN1pJJ