Pub-Guard-LLM: Detecting Fraudulent Biomedical Articles with Reliable Explanations

A significant and growing number of published scientific articles is found to involve fraudulent practices, posing a serious threat to the credibility and safety of research in fields such as medicine. We propose Pub-Guard-LLM, the first large language model-based system tailored to fraud detection of biomedical scientific articles. We provide three application modes for deploying Pub-Guard-LLM: vanilla reasoning, retrieval-augmented generation, and multi-agent debate. Each mode allows for textual explanations of predictions. To assess the performance of our system, we introduce an open-source benchmark, PubMed Retraction, comprising over 11K real-world biomedical articles, including metadata and retraction labels. We show that, across all modes, Pub-Guard-LLM consistently surpasses the performance of various baselines and provides more reliable explanations, namely explanations which are deemed more relevant and coherent than those generated by the baselines when evaluated by multiple assessment methods. By enhancing both detection performance and explainability in scientific fraud detection, Pub-Guard-LLM contributes to safeguarding research integrity with a novel, effective, open-source tool.

Contestable AI needs Computational Argumentation

AI has become pervasive in recent years, but state-of-the-art approaches predominantly neglect the need for AI systems to be contestable. Instead, contestability is advocated by AI guidelines (e.g. by the OECD) and regulation of automated decision-making (e.g. GDPR). In this position paper we explore how contestability can be achieved computationally in and for AI. We argue that contestable AI requires dynamic (human-machine and/or machine-machine) explainability and decision-making processes, whereby machines can (i) interact with humans and/or other machines to progressively explain their outputs and/or their reasoning as well as assess grounds for contestation provided by these humans and/or other machines, and (ii) revise their decision-making processes to redress any issues successfully raised during contestation. Given that much of the current AI landscape is tailored to static AIs, the need to accommodate contestability will require a radical rethinking, that, we argue, computational argumentation is ideally suited to support.

Argumentative Large Language Models for Explainable and Contestable Decision-Making

The diversity of knowledge encoded in large language models (LLMs) and their ability to apply this knowledge zero-shot in a range of settings makes them a promising candidate for use in decision-making. However, they are currently limited by their inability to reliably provide outputs which are explainable and contestable. In this paper, we attempt to reconcile these strengths and weaknesses by introducing a method for supplementing LLMs with argumentative reasoning. Concretely, we introduce argumentative LLMs, a method utilising LLMs to construct argumentation frameworks, which then serve as the basis for formal reasoning in decision-making. The interpretable nature of these argumentation frameworks and formal reasoning means that any decision made by the supplemented LLM may be naturally explained to, and contested by, humans. We demonstrate the effectiveness of argumentative LLMs experimentally in the decision-making task of claim verification. We obtain results that are competitive with, and in some cases surpass, comparable state-of-the-art techniques.