Pub-Guard-LLM: Detecting Fraudulent Biomedical Articles with Reliable Explanations

A significant and growing number of published scientific articles is found to involve fraudulent practices, posing a serious threat to the credibility and safety of research in fields such as medicine. We propose Pub-Guard-LLM, the first large language model-based system tailored to fraud detection of biomedical scientific articles. We provide three application modes for deploying Pub-Guard-LLM: vanilla reasoning, retrieval-augmented generation, and multi-agent debate. Each mode allows for textual explanations of predictions. To assess the performance of our system, we introduce an open-source benchmark, PubMed Retraction, comprising over 11K real-world biomedical articles, including metadata and retraction labels. We show that, across all modes, Pub-Guard-LLM consistently surpasses the performance of various baselines and provides more reliable explanations, namely explanations which are deemed more relevant and coherent than those generated by the baselines when evaluated by multiple assessment methods. By enhancing both detection performance and explainability in scientific fraud detection, Pub-Guard-LLM contributes to safeguarding research integrity with a novel, effective, open-source tool.

Collective Knowledge Graph Completion with Mutual Knowledge Distillation

Knowledge graph completion (KGC), the task of predicting missing information based on the existing relational data inside a knowledge graph (KG), has drawn significant attention in recent years. However, the predictive power of KGC methods is often limited by the completeness of the existing knowledge graphs from different sources and languages. In monolingual and multilingual settings, KGs are potentially complementary to each other. In this paper, we study the problem of multi-KG completion, where we focus on maximizing the collective knowledge from different KGs to alleviate the incompleteness of individual KGs. Specifically, we propose a novel method called CKGC-CKD that uses relation-aware graph convolutional network encoder models on both individual KGs and a large fused KG in which seed alignments between KGs are regarded as edges for message propagation. An additional mutual knowledge distillation mechanism is also employed to maximize the knowledge transfer between the models of "global" fused KG and the "local" individual KGs. Experimental results on multilingual datasets have shown that our method outperforms all state-of-the-art models in the KGC task.