Ethical Implementation of Artificial Intelligence to Select Embryos in In Vitro Fertilization

AI has the potential to revolutionize many areas of healthcare. Radiology, dermatology, and ophthalmology are some of the areas most likely to be impacted in the near future, and they have received significant attention from the broader research community. But AI techniques are now also starting to be used in in vitro fertilization (IVF), in particular for selecting which embryos to transfer to the woman. The contribution of AI to IVF is potentially significant, but must be done carefully and transparently, as the ethical issues are significant, in part because this field involves creating new people. We first give a brief introduction to IVF and review the use of AI for embryo selection. We discuss concerns with the interpretation of the reported results from scientific and practical perspectives. We then consider the broader ethical issues involved. We discuss in detail the problems that result from the use of black-box methods in this context and advocate strongly for the use of interpretable models. Importantly, there have been no published trials of clinical effectiveness, a problem in both the AI and IVF communities, and we therefore argue that clinical implementation at this point would be premature. Finally, we discuss ways for the broader AI community to become involved to ensure scientifically sound and ethically responsible development of AI in IVF.

Image Completion and Extrapolation with Contextual Cycle Consistency

Image Completion refers to the task of filling in the missing regions of an image and Image Extrapolation refers to the task of extending an image at its boundaries while keeping it coherent. Many recent works based on GAN have shown progress in addressing these problem statements but lack adaptability for these two cases, i.e. the neural network trained for the completion of interior masked images does not generalize well for extrapolating over the boundaries and vice-versa. In this paper, we present a technique to train both completion and extrapolation networks concurrently while benefiting each other. We demonstrate our method's efficiency in completing large missing regions and we show the comparisons with the contemporary state of the art baseline.

3DFR: A Swift 3D Feature Reductionist Framework for Scene Independent Change Detection

In this paper we propose an end-to-end swift 3D feature reductionist framework (3DFR) for scene independent change detection. The 3DFR framework consists of three feature streams: a swift 3D feature reductionist stream (AvFeat), a contemporary feature stream (ConFeat) and a temporal median feature map. These multilateral foreground/background features are further refined through an encoder-decoder network. As a result, the proposed framework not only detects temporal changes but also learns high-level appearance features. Thus, it incorporates the object semantics for effective change detection. Furthermore, the proposed framework is validated through a scene independent evaluation scheme in order to demonstrate the robustness and generalization capability of the network. The performance of the proposed method is evaluated on the benchmark CDnet 2014 dataset. The experimental results show that the proposed 3DFR network outperforms the state-of-the-art approaches.

A K-fold Method for Baseline Estimation in Policy Gradient Algorithms

The high variance issue in unbiased policy-gradient methods such as VPG and REINFORCE is typically mitigated by adding a baseline. However, the baseline fitting itself suffers from the underfitting or the overfitting problem. In this paper, we develop a K-fold method for baseline estimation in policy gradient algorithms. The parameter K is the baseline estimation hyperparameter that can adjust the bias-variance trade-off in the baseline estimates. We demonstrate the usefulness of our approach via two state-of-the-art policy gradient algorithms on three MuJoCo locomotive control tasks.