PedSleepMAE: Generative Model for Multimodal Pediatric Sleep Signals

Pediatric sleep is an important but often overlooked area in health informatics. We present PedSleepMAE, a generative model that fully leverages multimodal pediatric sleep signals including multichannel EEGs, respiratory signals, EOGs and EMG. This masked autoencoder-based model performs comparably to supervised learning models in sleep scoring and in the detection of apnea, hypopnea, EEG arousal and oxygen desaturation. Its embeddings are also shown to capture subtle differences in sleep signals coming from a rare genetic disorder. Furthermore, PedSleepMAE generates realistic signals that can be used for sleep segment retrieval, outlier detection, and missing channel imputation. This is the first general-purpose generative model trained on multiple types of pediatric sleep signals.

Electrocardiogram-Language Model for Few-Shot Question Answering with Meta Learning

Electrocardiogram (ECG) interpretation requires specialized expertise, often involving synthesizing insights from ECG signals with complex clinical queries posed in natural language. The scarcity of labeled ECG data coupled with the diverse nature of clinical inquiries presents a significant challenge for developing robust and adaptable ECG diagnostic systems. This work introduces a novel multimodal meta-learning method for few-shot ECG question answering, addressing the challenge of limited labeled data while leveraging the rich knowledge encoded within large language models (LLMs). Our LLM-agnostic approach integrates a pre-trained ECG encoder with a frozen LLM (e.g., LLaMA and Gemma) via a trainable fusion module, enabling the language model to reason about ECG data and generate clinically meaningful answers. Extensive experiments demonstrate superior generalization to unseen diagnostic tasks compared to supervised baselines, achieving notable performance even with limited ECG leads. For instance, in a 5-way 5-shot setting, our method using LLaMA-3.1-8B achieves accuracy of 84.6%, 77.3%, and 69.6% on single verify, choose and query question types, respectively. These results highlight the potential of our method to enhance clinical ECG interpretation by combining signal processing with the nuanced language understanding capabilities of LLMs, particularly in data-constrained scenarios.

RespLLM: Unifying Audio and Text with Multimodal LLMs for Generalized Respiratory Health Prediction

The high incidence and mortality rates associated with respiratory diseases underscores the importance of early screening. Machine learning models can automate clinical consultations and auscultation, offering vital support in this area. However, the data involved, spanning demographics, medical history, symptoms, and respiratory audio, are heterogeneous and complex. Existing approaches are insufficient and lack generalizability, as they typically rely on limited training data, basic fusion techniques, and task-specific models. In this paper, we propose RespLLM, a novel multimodal large language model (LLM) framework that unifies text and audio representations for respiratory health prediction. RespLLM leverages the extensive prior knowledge of pretrained LLMs and enables effective audio-text fusion through cross-modal attentions. Instruction tuning is employed to integrate diverse data from multiple sources, ensuring generalizability and versatility of the model. Experiments on five real-world datasets demonstrate that RespLLM outperforms leading baselines by an average of 4.6% on trained tasks, 7.9% on unseen datasets, and facilitates zero-shot predictions for new tasks. Our work lays the foundation for multimodal models that can perceive, listen to, and understand heterogeneous data, paving the way for scalable respiratory health diagnosis.

C-MELT: Contrastive Enhanced Masked Auto-Encoders for ECG-Language Pre-Training

Accurate interpretation of Electrocardiogram (ECG) signals is pivotal for diagnosing cardiovascular diseases. Integrating ECG signals with their accompanying textual reports holds immense potential to enhance clinical diagnostics through the combination of physiological data and qualitative insights. However, this integration faces significant challenges due to inherent modality disparities and the scarcity of labeled data for robust cross-modal learning. To address these obstacles, we propose C-MELT, a novel framework that pre-trains ECG and text data using a contrastive masked auto-encoder architecture. C-MELT uniquely combines the strengths of generative with enhanced discriminative capabilities to achieve robust cross-modal representations. This is accomplished through masked modality modeling, specialized loss functions, and an improved negative sampling strategy tailored for cross-modal alignment. Extensive experiments on five public datasets across diverse downstream tasks demonstrate that C-MELT significantly outperforms existing methods, achieving 15% and 2% increases in linear probing and zero-shot performance over state-of-the-art models, respectively. These results highlight the effectiveness of C-MELT, underscoring its potential to advance automated clinical diagnostics through multi-modal representations.

Electrocardiogram Report Generation and Question Answering via Retrieval-Augmented Self-Supervised Modeling

Interpreting electrocardiograms (ECGs) and generating comprehensive reports remain challenging tasks in cardiology, often requiring specialized expertise and significant time investment. To address these critical issues, we propose ECG-ReGen, a retrieval-based approach for ECG-to-text report generation and question answering. Our method leverages a self-supervised learning for the ECG encoder, enabling efficient similarity searches and report retrieval. By combining pre-training with dynamic retrieval and Large Language Model (LLM)-based refinement, ECG-ReGen effectively analyzes ECG data and answers related queries, with the potential of improving patient care. Experiments conducted on the PTB-XL and MIMIC-IV-ECG datasets demonstrate superior performance in both in-domain and cross-domain scenarios for report generation. Furthermore, our approach exhibits competitive performance on ECG-QA dataset compared to fully supervised methods when utilizing off-the-shelf LLMs for zero-shot question answering. This approach, effectively combining self-supervised encoder and LLMs, offers a scalable and efficient solution for accurate ECG interpretation, holding significant potential to enhance clinical decision-making.

Collaboratively Learning Federated Models from Noisy Decentralized Data

Federated learning (FL) has emerged as a prominent method for collaboratively training machine learning models using local data from edge devices, all while keeping data decentralized. However, accounting for the quality of data contributed by local clients remains a critical challenge in FL, as local data are often susceptible to corruption by various forms of noise and perturbations, which compromise the aggregation process and lead to a subpar global model. In this work, we focus on addressing the problem of noisy data in the input space, an under-explored area compared to the label noise. We propose a comprehensive assessment of client input in the gradient space, inspired by the distinct disparity observed between the density of gradient norm distributions of models trained on noisy and clean input data. Based on this observation, we introduce a straightforward yet effective approach to identify clients with low-quality data at the initial stage of FL. Furthermore, we propose a noise-aware FL aggregation method, namely Federated Noise-Sifting (FedNS), which can be used as a plug-in approach in conjunction with widely used FL strategies. Our extensive evaluation on diverse benchmark datasets under different federated settings demonstrates the efficacy of FedNS. Our method effortlessly integrates with existing FL strategies, enhancing the global model's performance by up to 13.68% in IID and 15.85% in non-IID settings when learning from noisy decentralized data.

Federated Learning with a Single Shared Image

Federated Learning (FL) enables multiple machines to collaboratively train a machine learning model without sharing of private training data. Yet, especially for heterogeneous models, a key bottleneck remains the transfer of knowledge gained from each client model with the server. One popular method, FedDF, uses distillation to tackle this task with the use of a common, shared dataset on which predictions are exchanged. However, in many contexts such a dataset might be difficult to acquire due to privacy and the clients might not allow for storage of a large shared dataset. To this end, in this paper, we introduce a new method that improves this knowledge distillation method to only rely on a single shared image between clients and server. In particular, we propose a novel adaptive dataset pruning algorithm that selects the most informative crops generated from only a single image. With this, we show that federated learning with distillation under a limited shared dataset budget works better by using a single image compared to multiple individual ones. Finally, we extend our approach to allow for training heterogeneous client architectures by incorporating a non-uniform distillation schedule and client-model mirroring on the server side.

A collection of the accepted papers for the Human-Centric Representation Learning workshop at AAAI 2024

This non-archival index is not complete, as some accepted papers chose to opt-out of inclusion. The list of all accepted papers is available on the workshop website.

Communication-Efficient Federated Learning through Adaptive Weight Clustering and Server-Side Distillation

Federated Learning (FL) is a promising technique for the collaborative training of deep neural networks across multiple devices while preserving data privacy. Despite its potential benefits, FL is hindered by excessive communication costs due to repeated server-client communication during training. To address this challenge, model compression techniques, such as sparsification and weight clustering are applied, which often require modifying the underlying model aggregation schemes or involve cumbersome hyperparameter tuning, with the latter not only adjusts the model's compression rate but also limits model's potential for continuous improvement over growing data. In this paper, we propose FedCompress, a novel approach that combines dynamic weight clustering and server-side knowledge distillation to reduce communication costs while learning highly generalizable models. Through a comprehensive evaluation on diverse public datasets, we demonstrate the efficacy of our approach compared to baselines in terms of communication costs and inference speed. We will make our implementation public upon acceptance.

Learning under Label Noise through Few-Shot Human-in-the-Loop Refinement

Wearable technologies enable continuous monitoring of various health metrics, such as physical activity, heart rate, sleep, and stress levels. A key challenge with wearable data is obtaining quality labels. Unlike modalities like video where the videos themselves can be effectively used to label objects or events, wearable data do not contain obvious cues about the physical manifestation of the users and usually require rich metadata. As a result, label noise can become an increasingly thorny issue when labeling such data. In this paper, we propose a novel solution to address noisy label learning, entitled Few-Shot Human-in-the-Loop Refinement (FHLR). Our method initially learns a seed model using weak labels. Next, it fine-tunes the seed model using a handful of expert corrections. Finally, it achieves better generalizability and robustness by merging the seed and fine-tuned models via weighted parameter averaging. We evaluate our approach on four challenging tasks and datasets, and compare it against eight competitive baselines designed to deal with noisy labels. We show that FHLR achieves significantly better performance when learning from noisy labels and achieves state-of-the-art by a large margin, with up to 19% accuracy improvement under symmetric and asymmetric noise. Notably, we find that FHLR is particularly robust to increased label noise, unlike prior works that suffer from severe performance degradation. Our work not only achieves better generalization in high-stakes health sensing benchmarks but also sheds light on how noise affects commonly-used models.