Boundary-Guided Learning for Gene Expression Prediction in Spatial Transcriptomics

Spatial transcriptomics (ST) has emerged as an advanced technology that provides spatial context to gene expression. Recently, deep learning-based methods have shown the capability to predict gene expression from WSI data using ST data. Existing approaches typically extract features from images and the neighboring regions using pretrained models, and then develop methods to fuse this information to generate the final output. However, these methods often fail to account for the cellular structure similarity, cellular density and the interactions within the microenvironment. In this paper, we propose a framework named BG-TRIPLEX, which leverages boundary information extracted from pathological images as guiding features to enhance gene expression prediction from WSIs. Specifically, our model consists of three branches: the spot, in-context and global branches. In the spot and in-context branches, boundary information, including edge and nuclei characteristics, is extracted using pretrained models. These boundary features guide the learning of cellular morphology and the characteristics of microenvironment through Multi-Head Cross-Attention. Finally, these features are integrated with global features to predict the final output. Extensive experiments were conducted on three public ST datasets. The results demonstrate that our BG-TRIPLEX consistently outperforms existing methods in terms of Pearson Correlation Coefficient (PCC). This method highlights the crucial role of boundary features in understanding the complex interactions between WSI and gene expression, offering a promising direction for future research.

One-Shot Pose-Driving Face Animation Platform

The objective of face animation is to generate dynamic and expressive talking head videos from a single reference face, utilizing driving conditions derived from either video or audio inputs. Current approaches often require fine-tuning for specific identities and frequently fail to produce expressive videos due to the limited effectiveness of Wav2Pose modules. To facilitate the generation of one-shot and more consecutive talking head videos, we refine an existing Image2Video model by integrating a Face Locator and Motion Frame mechanism. We subsequently optimize the model using extensive human face video datasets, significantly enhancing its ability to produce high-quality and expressive talking head videos. Additionally, we develop a demo platform using the Gradio framework, which streamlines the process, enabling users to quickly create customized talking head videos.

Scene Style Text Editing

In this work, we propose a task called "Scene Style Text Editing (SSTE)", changing the text content as well as the text style of the source image while keeping the original text scene. Existing methods neglect to fine-grained adjust the style of the foreground text, such as its rotation angle, color, and font type. To tackle this task, we propose a quadruple framework named "QuadNet" to embed and adjust foreground text styles in the latent feature space. Specifically, QuadNet consists of four parts, namely background inpainting, style encoder, content encoder, and fusion generator. The background inpainting erases the source text content and recovers the appropriate background with a highly authentic texture. The style encoder extracts the style embedding of the foreground text. The content encoder provides target text representations in the latent feature space to implement the content edits. The fusion generator combines the information yielded from the mentioned parts and generates the rendered text images. Practically, our method is capable of performing promisingly on real-world datasets with merely string-level annotation. To the best of our knowledge, our work is the first to finely manipulate the foreground text content and style by deeply semantic editing in the latent feature space. Extensive experiments demonstrate that QuadNet has the ability to generate photo-realistic foreground text and avoid source text shadows in real-world scenes when editing text content.

A Survey on Deep Neural Network Partition over Cloud, Edge and End Devices

Deep neural network (DNN) partition is a research problem that involves splitting a DNN into multiple parts and offloading them to specific locations. Because of the recent advancement in multi-access edge computing and edge intelligence, DNN partition has been considered as a powerful tool for improving DNN inference performance when the computing resources of edge and end devices are limited and the remote transmission of data from these devices to clouds is costly. This paper provides a comprehensive survey on the recent advances and challenges in DNN partition approaches over the cloud, edge, and end devices based on a detailed literature collection. We review how DNN partition works in various application scenarios, and provide a unified mathematical model of the DNN partition problem. We developed a five-dimensional classification framework for DNN partition approaches, consisting of deployment locations, partition granularity, partition constraints, optimization objectives, and optimization algorithms. Each existing DNN partition approache can be perfectly defined in this framework by instantiating each dimension into specific values. In addition, we suggest a set of metrics for comparing and evaluating the DNN partition approaches. Based on this, we identify and discuss research challenges that have not yet been investigated or fully addressed. We hope that this work helps DNN partition researchers by highlighting significant future research directions in this domain.