LymphAtlas- A Unified Multimodal Lymphoma Imaging Repository Delivering AI-Enhanced Diagnostic Insight

This study integrates PET metabolic information with CT anatomical structures to establish a 3D multimodal segmentation dataset for lymphoma based on whole-body FDG PET/CT examinations, which bridges the gap of the lack of standardised multimodal segmentation datasets in the field of haematological malignancies. We retrospectively collected 483 examination datasets acquired between March 2011 and May 2024, involving 220 patients (106 non-Hodgkin lymphoma, 42 Hodgkin lymphoma); all data underwent ethical review and were rigorously de-identified. Complete 3D structural information was preserved during data acquisition, preprocessing and annotation, and a high-quality dataset was constructed based on the nnUNet format. By systematic technical validation and evaluation of the preprocessing process, annotation quality and automatic segmentation algorithm, the deep learning model trained based on this dataset is verified to achieve accurate segmentation of lymphoma lesions in PET/CT images with high accuracy, good robustness and reproducibility, which proves the applicability and stability of this dataset in accurate segmentation and quantitative analysis. The deep fusion of PET/CT images achieved with this dataset not only significantly improves the accurate portrayal of the morphology, location and metabolic features of tumour lesions, but also provides solid data support for early diagnosis, clinical staging and personalized treatment, and promotes the development of automated image segmentation and precision medicine based on deep learning. The dataset and related resources are available at https://github.com/SuperD0122/LymphAtlas-.

PINN-EMFNet: PINN-based and Enhanced Multi-Scale Feature Fusion Network for Breast Ultrasound Images Segmentation

With the rapid development of deep learning and computer vision technologies, medical image segmentation plays a crucial role in the early diagnosis of breast cancer. However, due to the characteristics of breast ultrasound images, such as low contrast, speckle noise, and the highly diverse morphology of tumors, existing segmentation methods exhibit significant limitations in terms of accuracy and robustness. To address these challenges, this study proposes a PINN-based and Enhanced Multi-Scale Feature Fusion Network. The network introduces a Hierarchical Aggregation Encoder in the backbone, which efficiently integrates and globally models multi-scale features through several structural innovations and a novel PCAM module. In the decoder section, a Multi-Scale Feature Refinement Decoder is employed, which, combined with a Multi-Scale Supervision Mechanism and a correction module, significantly improves segmentation accuracy and adaptability. Additionally, the loss function incorporating the PINN mechanism introduces physical constraints during the segmentation process, enhancing the model's ability to accurately delineate tumor boundaries. Comprehensive evaluations on two publicly available breast ultrasound datasets, BUSIS and BUSI, demonstrate that the proposed method outperforms previous segmentation approaches in terms of segmentation accuracy and robustness, particularly under conditions of complex noise and low contrast, effectively improving the accuracy and reliability of tumor segmentation. This method provides a more precise and robust solution for computer-aided diagnosis of breast ultrasound images.

Imp: Highly Capable Large Multimodal Models for Mobile Devices

By harnessing the capabilities of large language models (LLMs), recent large multimodal models (LMMs) have shown remarkable versatility in open-world multimodal understanding. Nevertheless, they are usually parameter-heavy and computation-intensive, thus hindering their applicability in resource-constrained scenarios. To this end, several lightweight LMMs have been proposed successively to maximize the capabilities under constrained scale (e.g., 3B). Despite the encouraging results achieved by these methods, most of them only focus on one or two aspects of the design space, and the key design choices that influence model capability have not yet been thoroughly investigated. In this paper, we conduct a systematic study for lightweight LMMs from the aspects of model architecture, training strategy, and training data. Based on our findings, we obtain Imp -- a family of highly capable LMMs at the 2B-4B scales. Notably, our Imp-3B model steadily outperforms all the existing lightweight LMMs of similar size, and even surpasses the state-of-the-art LMMs at the 13B scale. With low-bit quantization and resolution reduction techniques, our Imp model can be deployed on a Qualcomm Snapdragon 8Gen3 mobile chip with a high inference speed of about 13 tokens/s.

ZS-SRT: An Efficient Zero-Shot Super-Resolution Training Method for Neural Radiance Fields

Neural Radiance Fields (NeRF) have achieved great success in the task of synthesizing novel views that preserve the same resolution as the training views. However, it is challenging for NeRF to synthesize high-quality high-resolution novel views with low-resolution training data. To solve this problem, we propose a zero-shot super-resolution training framework for NeRF. This framework aims to guide the NeRF model to synthesize high-resolution novel views via single-scene internal learning rather than requiring any external high-resolution training data. Our approach consists of two stages. First, we learn a scene-specific degradation mapping by performing internal learning on a pretrained low-resolution coarse NeRF. Second, we optimize a super-resolution fine NeRF by conducting inverse rendering with our mapping function so as to backpropagate the gradients from low-resolution 2D space into the super-resolution 3D sampling space. Then, we further introduce a temporal ensemble strategy in the inference phase to compensate for the scene estimation errors. Our method is featured on two points: (1) it does not consume high-resolution views or additional scene data to train super-resolution NeRF; (2) it can speed up the training process by adopting a coarse-to-fine strategy. By conducting extensive experiments on public datasets, we have qualitatively and quantitatively demonstrated the effectiveness of our method.