Comparative Analysis of Pre-trained Deep Learning Models and DINOv2 for Cushing's Syndrome Diagnosis in Facial Analysis

Cushing's syndrome is a condition caused by excessive glucocorticoid secretion from the adrenal cortex, often manifesting with moon facies and plethora, making facial data crucial for diagnosis. Previous studies have used pre-trained convolutional neural networks (CNNs) for diagnosing Cushing's syndrome using frontal facial images. However, CNNs are better at capturing local features, while Cushing's syndrome often presents with global facial features. Transformer-based models like ViT and SWIN, which utilize self-attention mechanisms, can better capture long-range dependencies and global features. Recently, DINOv2, a foundation model based on visual Transformers, has gained interest. This study compares the performance of various pre-trained models, including CNNs, Transformer-based models, and DINOv2, in diagnosing Cushing's syndrome. We also analyze gender bias and the impact of freezing mechanisms on DINOv2. Our results show that Transformer-based models and DINOv2 outperformed CNNs, with ViT achieving the highest F1 score of 85.74%. Both the pre-trained model and DINOv2 had higher accuracy for female samples. DINOv2 also showed improved performance when freezing parameters. In conclusion, Transformer-based models and DINOv2 are effective for Cushing's syndrome classification.

MobileNetV2: A lightweight classification model for home-based sleep apnea screening

This study proposes a novel lightweight neural network model leveraging features extracted from electrocardiogram (ECG) and respiratory signals for early OSA screening. ECG signals are used to generate feature spectrograms to predict sleep stages, while respiratory signals are employed to detect sleep-related breathing abnormalities. By integrating these predictions, the method calculates the apnea-hypopnea index (AHI) with enhanced accuracy, facilitating precise OSA diagnosis. The method was validated on three publicly available sleep apnea databases: the Apnea-ECG database, the UCDDB dataset, and the MIT-BIH Polysomnographic database. Results showed an overall OSA detection accuracy of 0.978, highlighting the model's robustness. Respiratory event classification achieved an accuracy of 0.969 and an area under the receiver operating characteristic curve (ROC-AUC) of 0.98. For sleep stage classification, in UCDDB dataset, the ROC-AUC exceeded 0.85 across all stages, with recall for Sleep reaching 0.906 and specificity for REM and Wake states at 0.956 and 0.937, respectively. This study underscores the potential of integrating lightweight neural networks with multi-signal analysis for accurate, portable, and cost-effective OSA screening, paving the way for broader adoption in home-based and wearable health monitoring systems.

Semantic-Rearrangement-Based Multi-Level Alignment for Domain Generalized Segmentation

Domain generalized semantic segmentation is an essential computer vision task, for which models only leverage source data to learn the capability of generalized semantic segmentation towards the unseen target domains. Previous works typically address this challenge by global style randomization or feature regularization. In this paper, we argue that given the observation that different local semantic regions perform different visual characteristics from the source domain to the target domain, methods focusing on global operations are hard to capture such regional discrepancies, thus failing to construct domain-invariant representations with the consistency from local to global level. Therefore, we propose the Semantic-Rearrangement-based Multi-Level Alignment (SRMA) to overcome this problem. SRMA first incorporates a Semantic Rearrangement Module (SRM), which conducts semantic region randomization to enhance the diversity of the source domain sufficiently. A Multi-Level Alignment module (MLA) is subsequently proposed with the help of such diversity to establish the global-regional-local consistent domain-invariant representations. By aligning features across randomized samples with domain-neutral knowledge at multiple levels, SRMA provides a more robust way to handle the source-target domain gap. Extensive experiments demonstrate the superiority of SRMA over the current state-of-the-art works on various benchmarks.