Med-PMC: Medical Personalized Multi-modal Consultation with a Proactive Ask-First-Observe-Next Paradigm

The application of the Multi-modal Large Language Models (MLLMs) in medical clinical scenarios remains underexplored. Previous benchmarks only focus on the capacity of the MLLMs in medical visual question-answering (VQA) or report generation and fail to assess the performance of the MLLMs on complex clinical multi-modal tasks. In this paper, we propose a novel Medical Personalized Multi-modal Consultation (Med-PMC) paradigm to evaluate the clinical capacity of the MLLMs. Med-PMC builds a simulated clinical environment where the MLLMs are required to interact with a patient simulator to complete the multi-modal information-gathering and decision-making task. Specifically, the patient simulator is decorated with personalized actors to simulate diverse patients in real scenarios. We conduct extensive experiments to access 12 types of MLLMs, providing a comprehensive view of the MLLMs' clinical performance. We found that current MLLMs fail to gather multimodal information and show potential bias in the decision-making task when consulted with the personalized patient simulators. Further analysis demonstrates the effectiveness of Med-PMC, showing the potential to guide the development of robust and reliable clinical MLLMs. Code and data are available at https://github.com/LiuHC0428/Med-PMC.

Decoding Linguistic Representations of Human Brain

Language, as an information medium created by advanced organisms, has always been a concern of neuroscience regarding how it is represented in the brain. Decoding linguistic representations in the evoked brain has shown groundbreaking achievements, thanks to the rapid improvement of neuroimaging, medical technology, life sciences and artificial intelligence. In this work, we present a taxonomy of brain-to-language decoding of both textual and speech formats. This work integrates two types of research: neuroscience focusing on language understanding and deep learning-based brain decoding. Generating discernible language information from brain activity could not only help those with limited articulation, especially amyotrophic lateral sclerosis (ALS) patients but also open up a new way for the next generation's brain-computer interface (BCI). This article will help brain scientists and deep-learning researchers to gain a bird's eye view of fine-grained language perception, and thus facilitate their further investigation and research of neural process and language decoding.

Towards an End-to-End Framework for Invasive Brain Signal Decoding with Large Language Models

In this paper, we introduce a groundbreaking end-to-end (E2E) framework for decoding invasive brain signals, marking a significant advancement in the field of speech neuroprosthesis. Our methodology leverages the comprehensive reasoning abilities of large language models (LLMs) to facilitate direct decoding. By fully integrating LLMs, we achieve results comparable to the state-of-the-art cascade models. Our findings underscore the immense potential of E2E frameworks in speech neuroprosthesis, particularly as the technology behind brain-computer interfaces (BCIs) and the availability of relevant datasets continue to evolve. This work not only showcases the efficacy of combining LLMs with E2E decoding for enhancing speech neuroprosthesis but also sets a new direction for future research in BCI applications, underscoring the impact of LLMs in decoding complex neural signals for communication restoration. Code will be made available at https://github.com/FsFrancis15/BrainLLM.

M$^3$AV: A Multimodal, Multigenre, and Multipurpose Audio-Visual Academic Lecture Dataset

Publishing open-source academic video recordings is an emergent and prevalent approach to sharing knowledge online. Such videos carry rich multimodal information including speech, the facial and body movements of the speakers, as well as the texts and pictures in the slides and possibly even the papers. Although multiple academic video datasets have been constructed and released, few of them support both multimodal content recognition and understanding tasks, which is partially due to the lack of high-quality human annotations. In this paper, we propose a novel multimodal, multigenre, and multipurpose audio-visual academic lecture dataset (M$^3$AV), which has almost 367 hours of videos from five sources covering computer science, mathematics, and medical and biology topics. With high-quality human annotations of the spoken and written words, in particular high-valued name entities, the dataset can be used for multiple audio-visual recognition and understanding tasks. Evaluations performed on contextual speech recognition, speech synthesis, and slide and script generation tasks demonstrate that the diversity of M$^3$AV makes it a challenging dataset.

Post-decoder Biasing for End-to-End Speech Recognition of Multi-turn Medical Interview

End-to-end (E2E) approach is gradually replacing hybrid models for automatic speech recognition (ASR) tasks. However, the optimization of E2E models lacks an intuitive method for handling decoding shifts, especially in scenarios with a large number of domain-specific rare words that hold specific important meanings. Furthermore, the absence of knowledge-intensive speech datasets in academia has been a significant limiting factor, and the commonly used speech corpora exhibit significant disparities with realistic conversation. To address these challenges, we present Medical Interview (MED-IT), a multi-turn consultation speech dataset that contains a substantial number of knowledge-intensive named entities. We also explore methods to enhance the recognition performance of rare words for E2E models. We propose a novel approach, post-decoder biasing, which constructs a transform probability matrix based on the distribution of training transcriptions. This guides the model to prioritize recognizing words in the biasing list. In our experiments, for subsets of rare words appearing in the training speech between 10 and 20 times, and between 1 and 5 times, the proposed method achieves a relative improvement of 9.3% and 5.1%, respectively.

MM-SAP: A Comprehensive Benchmark for Assessing Self-Awareness of Multimodal Large Language Models in Perception

Multimodal Large Language Models (MLLMs) have shown their remarkable abilities in visual perception and understanding recently. However, how to comprehensively evaluate the capabilities of MLLMs remains a challenge. Most of the existing benchmarks predominantly focus on assessing perception, cognition, and reasoning, neglecting the abilities of self-awareness, referring to the model's recognition of its own capability boundary. In our study, we focus on self-awareness in image perception and introduce the knowledge quadrant for MLLMs, which clearly defines the knowns and unknowns in perception. Based on this, we propose a novel benchmark specifically designed to evaluate the Self-Aware capabilities in Perception for MLLMs(MM-SAP). MM-SAP encompasses three distinct sub-datasets, each focusing on different aspects of self-awareness. We evaluated eight well-known MLLMs using MM-SAP, analyzing their self-awareness and providing detailed insights. Code and data are available at https://github.com/YHWmz/MM-SAP

LibriSQA: Advancing Free-form and Open-ended Spoken Question Answering with a Novel Dataset and Framework

While Large Language Models (LLMs) have demonstrated commendable performance across a myriad of domains and tasks, existing LLMs still exhibit a palpable deficit in handling multimodal functionalities, especially for the Spoken Question Answering (SQA) task which necessitates precise alignment and deep interaction between speech and text features. To address the SQA challenge on LLMs, we initially curated the free-form and open-ended LibriSQA dataset from Librispeech, comprising Part I with natural conversational formats and Part II encompassing multiple-choice questions followed by answers and analytical segments. Both parts collectively include 107k SQA pairs that cover various topics. Given the evident paucity of existing speech-text LLMs, we propose a lightweight, end-to-end framework to execute the SQA task on the LibriSQA, witnessing significant results. By reforming ASR into the SQA format, we further substantiate our framework's capability in handling ASR tasks. Our empirical findings bolster the LLMs' aptitude for aligning and comprehending multimodal information, paving the way for the development of universal multimodal LLMs. The dataset and demo can be found at https://github.com/ZihanZhaoSJTU/LibriSQA.