AI-driven View Guidance System in Intra-cardiac Echocardiography Imaging

Intra-cardiac Echocardiography (ICE) is a crucial imaging modality used in electrophysiology (EP) and structural heart disease (SHD) interventions, providing real-time, high-resolution views from within the heart. Despite its advantages, effective manipulation of the ICE catheter requires significant expertise, which can lead to inconsistent outcomes, particularly among less experienced operators. To address this challenge, we propose an AI-driven closed-loop view guidance system with human-in-the-loop feedback, designed to assist users in navigating ICE imaging without requiring specialized knowledge. Our method models the relative position and orientation vectors between arbitrary views and clinically defined ICE views in a spatial coordinate system, guiding users on how to manipulate the ICE catheter to transition from the current view to the desired view over time. Operating in a closed-loop configuration, the system continuously predicts and updates the necessary catheter manipulations, ensuring seamless integration into existing clinical workflows. The effectiveness of the proposed system is demonstrated through a simulation-based evaluation, achieving an 89% success rate with the 6532 test dataset, highlighting its potential to improve the accuracy and efficiency of ICE imaging procedures.

ExploreSelf: Fostering User-driven Exploration and Reflection on Personal Challenges with Adaptive Guidance by Large Language Models

Expressing stressful experiences in words is proven to improve mental and physical health, but individuals often disengage with writing interventions as they struggle to organize their thoughts and emotions. Reflective prompts have been used to provide direction, and large language models (LLMs) have demonstrated the potential to provide tailored guidance. Current systems often limit users' flexibility to direct their reflections. We thus present ExploreSelf, an LLM-driven application designed to empower users to control their reflective journey. ExploreSelf allows users to receive adaptive support through dynamically generated questions. Through an exploratory study with 19 participants, we examine how participants explore and reflect on personal challenges using ExploreSelf. Our findings demonstrate that participants valued the balance between guided support and freedom to control their reflective journey, leading to deeper engagement and insight. Building on our findings, we discuss implications for designing LLM-driven tools that promote user empowerment through effective reflective practices.

AACessTalk: Fostering Communication between Minimally Verbal Autistic Children and Parents with Contextual Guidance and Card Recommendation

As minimally verbal autistic (MVA) children communicate with parents through few words and nonverbal cues, parents often struggle to encourage their children to express subtle emotions and needs and to grasp their nuanced signals. We present AACessTalk, a tablet-based, AI-mediated communication system that facilitates meaningful exchanges between an MVA child and a parent. AACessTalk provides real-time guides to the parent to engage the child in conversation and, in turn, recommends contextual vocabulary cards to the child. Through a two-week deployment study with 11 MVA child-parent dyads, we examine how AACessTalk fosters everyday conversation practice and mutual engagement. Our findings show high engagement from all dyads, leading to increased frequency of conversation and turn-taking. AACessTalk also encouraged parents to explore their own interaction strategies and empowered the children to have more agency in communication. We discuss the implications of designing technologies for balanced communication dynamics in parent-MVA child interaction.

ELMI: Interactive and Intelligent Sign Language Translation of Lyrics for Song Signing

d/Deaf and hearing song-signers become prevalent on video-sharing platforms, but translating songs into sign language remains cumbersome and inaccessible. Our formative study revealed the challenges song-signers face, including semantic, syntactic, expressive, and rhythmic considerations in translations. We present ELMI, an accessible song-signing tool that assists in translating lyrics into sign language. ELMI enables users to edit glosses line-by-line, with real-time synced lyric highlighting and music video snippets. Users can also chat with a large language model-driven AI to discuss meaning, glossing, emoting, and timing. Through an exploratory study with 13 song-signers, we examined how ELMI facilitates their workflows and how song-signers leverage and receive an LLM-driven chat for translation. Participants successfully adopted ELMI to song-signing, with active discussions on the fly. They also reported improved confidence and independence in their translations, finding ELMI encouraging, constructive, and informative. We discuss design implications for leveraging LLMs in culturally sensitive song-signing translations.

Goal-conditioned reinforcement learning for ultrasound navigation guidance

Transesophageal echocardiography (TEE) plays a pivotal role in cardiology for diagnostic and interventional procedures. However, using it effectively requires extensive training due to the intricate nature of image acquisition and interpretation. To enhance the efficiency of novice sonographers and reduce variability in scan acquisitions, we propose a novel ultrasound (US) navigation assistance method based on contrastive learning as goal-conditioned reinforcement learning (GCRL). We augment the previous framework using a novel contrastive patient batching method (CPB) and a data-augmented contrastive loss, both of which we demonstrate are essential to ensure generalization to anatomical variations across patients. The proposed framework enables navigation to both standard diagnostic as well as intricate interventional views with a single model. Our method was developed with a large dataset of 789 patients and obtained an average error of 6.56 mm in position and 9.36 degrees in angle on a testing dataset of 140 patients, which is competitive or superior to models trained on individual views. Furthermore, we quantitatively validate our method's ability to navigate to interventional views such as the Left Atrial Appendage (LAA) view used in LAA closure. Our approach holds promise in providing valuable guidance during transesophageal ultrasound examinations, contributing to the advancement of skill acquisition for cardiac ultrasound practitioners.

Understanding the Impact of Long-Term Memory on Self-Disclosure with Large Language Model-Driven Chatbots for Public Health Intervention

Recent large language models (LLMs) offer the potential to support public health monitoring by facilitating health disclosure through open-ended conversations but rarely preserve the knowledge gained about individuals across repeated interactions. Augmenting LLMs with long-term memory (LTM) presents an opportunity to improve engagement and self-disclosure, but we lack an understanding of how LTM impacts people's interaction with LLM-driven chatbots in public health interventions. We examine the case of CareCall -- an LLM-driven voice chatbot with LTM -- through the analysis of 1,252 call logs and interviews with nine users. We found that LTM enhanced health disclosure and fostered positive perceptions of the chatbot by offering familiarity. However, we also observed challenges in promoting self-disclosure through LTM, particularly around addressing chronic health conditions and privacy concerns. We discuss considerations for LTM integration in LLM-driven chatbots for public health monitoring, including carefully deciding what topics need to be remembered in light of public health goals.

Cardiac ultrasound simulation for autonomous ultrasound navigation

Ultrasound is well-established as an imaging modality for diagnostic and interventional purposes. However, the image quality varies with operator skills as acquiring and interpreting ultrasound images requires extensive training due to the imaging artefacts, the range of acquisition parameters and the variability of patient anatomies. Automating the image acquisition task could improve acquisition reproducibility and quality but training such an algorithm requires large amounts of navigation data, not saved in routine examinations. Thus, we propose a method to generate large amounts of ultrasound images from other modalities and from arbitrary positions, such that this pipeline can later be used by learning algorithms for navigation. We present a novel simulation pipeline which uses segmentations from other modalities, an optimized volumetric data representation and GPU-accelerated Monte Carlo path tracing to generate view-dependent and patient-specific ultrasound images. We extensively validate the correctness of our pipeline with a phantom experiment, where structures' sizes, contrast and speckle noise properties are assessed. Furthermore, we demonstrate its usability to train neural networks for navigation in an echocardiography view classification experiment by generating synthetic images from more than 1000 patients. Networks pre-trained with our simulations achieve significantly superior performance in settings where large real datasets are not available, especially for under-represented classes. The proposed approach allows for fast and accurate patient-specific ultrasound image generation, and its usability for training networks for navigation-related tasks is demonstrated.

MindfulDiary: Harnessing Large Language Model to Support Psychiatric Patients' Journaling

In the mental health domain, Large Language Models (LLMs) offer promising new opportunities, though their inherent complexity and low controllability have raised questions about their suitability in clinical settings. We present MindfulDiary, a mobile journaling app incorporating an LLM to help psychiatric patients document daily experiences through conversation. Designed in collaboration with mental health professionals (MHPs), MindfulDiary takes a state-based approach to safely comply with the experts' guidelines while carrying on free-form conversations. Through a four-week field study involving 28 patients with major depressive disorder and five psychiatrists, we found that MindfulDiary supported patients in consistently enriching their daily records and helped psychiatrists better empathize with their patients through an understanding of their thoughts and daily contexts. Drawing on these findings, we discuss the implications of leveraging LLMs in the mental health domain, bridging the technical feasibility and their integration into clinical settings.

EvalLM: Interactive Evaluation of Large Language Model Prompts on User-Defined Criteria

By simply composing prompts, developers can prototype novel generative applications with Large Language Models (LLMs). To refine prototypes into products, however, developers must iteratively revise prompts by evaluating outputs to diagnose weaknesses. Formative interviews (N=8) revealed that developers invest significant effort in manually evaluating outputs as they assess context-specific and subjective criteria. We present EvalLM, an interactive system for iteratively refining prompts by evaluating multiple outputs on user-defined criteria. By describing criteria in natural language, users can employ the system's LLM-based evaluator to get an overview of where prompts excel or fail, and improve these based on the evaluator's feedback. A comparative study (N=12) showed that EvalLM, when compared to manual evaluation, helped participants compose more diverse criteria, examine twice as many outputs, and reach satisfactory prompts with 59% fewer revisions. Beyond prompts, our work can be extended to augment model evaluation and alignment in specific application contexts.

PlanFitting: Tailoring Personalized Exercise Plans with Large Language Models

A personally tailored exercise regimen is crucial to ensuring sufficient physical activities, yet challenging to create as people have complex schedules and considerations and the creation of plans often requires iterations with experts. We present PlanFitting, a conversational AI that assists in personalized exercise planning. Leveraging generative capabilities of large language models, PlanFitting enables users to describe various constraints and queries in natural language, thereby facilitating the creation and refinement of their weekly exercise plan to suit their specific circumstances while staying grounded in foundational principles. Through a user study where participants (N=18) generated a personalized exercise plan using PlanFitting and expert planners (N=3) evaluated these plans, we identified the potential of PlanFitting in generating personalized, actionable, and evidence-based exercise plans. We discuss future design opportunities for AI assistants in creating plans that better comply with exercise principles and accommodate personal constraints.