PLATYPUS: Progressive Local Surface Estimator for Arbitrary-Scale Point Cloud Upsampling

3D point clouds are increasingly vital for applications like autonomous driving and robotics, yet the raw data captured by sensors often suffer from noise and sparsity, creating challenges for downstream tasks. Consequently, point cloud upsampling becomes essential for improving density and uniformity, with recent approaches showing promise by projecting randomly generated query points onto the underlying surface of sparse point clouds. However, these methods often result in outliers, non-uniformity, and difficulties in handling regions with high curvature and intricate structures. In this work, we address these challenges by introducing the Progressive Local Surface Estimator (PLSE), which more effectively captures local features in complex regions through a curvature-based sampling technique that selectively targets high-curvature areas. Additionally, we incorporate a curriculum learning strategy that leverages the curvature distribution within the point cloud to naturally assess the sample difficulty, enabling curriculum learning on point cloud data for the first time. The experimental results demonstrate that our approach significantly outperforms existing methods, achieving high-quality, dense point clouds with superior accuracy and detail.

Disentangling Disentangled Representations: Towards Improved Latent Units via Diffusion Models

Disentangled representation learning (DRL) aims to break down observed data into core intrinsic factors for a profound understanding of the data. In real-world scenarios, manually defining and labeling these factors are non-trivial, making unsupervised methods attractive. Recently, there have been limited explorations of utilizing diffusion models (DMs), which are already mainstream in generative modeling, for unsupervised DRL. They implement their own inductive bias to ensure that each latent unit input to the DM expresses only one distinct factor. In this context, we design Dynamic Gaussian Anchoring to enforce attribute-separated latent units for more interpretable DRL. This unconventional inductive bias explicitly delineates the decision boundaries between attributes while also promoting the independence among latent units. Additionally, we also propose Skip Dropout technique, which easily modifies the denoising U-Net to be more DRL-friendly, addressing its uncooperative nature with the disentangling feature extractor. Our methods, which carefully consider the latent unit semantics and the distinct DM structure, enhance the practicality of DM-based disentangled representations, demonstrating state-of-the-art disentanglement performance on both synthetic and real data, as well as advantages in downstream tasks.

DragText: Rethinking Text Embedding in Point-based Image Editing

Point-based image editing enables accurate and flexible control through content dragging. However, the role of text embedding in the editing process has not been thoroughly investigated. A significant aspect that remains unexplored is the interaction between text and image embeddings. In this study, we show that during the progressive editing of an input image in a diffusion model, the text embedding remains constant. As the image embedding increasingly diverges from its initial state, the discrepancy between the image and text embeddings presents a significant challenge. Moreover, we found that the text prompt significantly influences the dragging process, particularly in maintaining content integrity and achieving the desired manipulation. To utilize these insights, we propose DragText, which optimizes text embedding in conjunction with the dragging process to pair with the modified image embedding. Simultaneously, we regularize the text optimization process to preserve the integrity of the original text prompt. Our approach can be seamlessly integrated with existing diffusion-based drag methods with only a few lines of code.

Parameter Efficient Fine Tuning for Multi-scanner PET to PET Reconstruction

Reducing scan time in Positron Emission Tomography (PET) imaging while maintaining high-quality images is crucial for minimizing patient discomfort and radiation exposure. Due to the limited size of datasets and distribution discrepancy across scanners in medical imaging, fine-tuning in a parameter-efficient and effective manner is on the rise. Motivated by the potential of Parameter-Efficient Fine-Tuning (PEFT), we aim to address these issues by effectively leveraging PEFT to improve limited data and GPU resource issues in multi-scanner setups. In this paper, we introduce PETITE, Parameter-Efficient Fine-Tuning for MultI-scanner PET to PET REconstruction that uses fewer than 1% of the parameters. To the best of our knowledge, this study is the first to systematically explore the efficacy of diverse PEFT techniques in medical imaging reconstruction tasks via prevalent encoder-decoder-type deep models. This investigation, in particular, brings intriguing insights into PETITE as we show further improvements by treating encoder and decoder separately and mixing different PEFT methods, namely, Mix-PEFT. Using multi-scanner PET datasets comprised of five different scanners, we extensively test the cross-scanner PET scan time reduction performances (i.e., a model pre-trained on one scanner is fine-tuned on a different scanner) of 21 feasible Mix-PEFT combinations to derive optimal PETITE. We show that training with less than 1% parameters using PETITE performs on par with full fine-tuning (i.e., 100% parameter)

Slice-Consistent 3D Volumetric Brain CT-to-MRI Translation with 2D Brownian Bridge Diffusion Model

In neuroimaging, generally, brain CT is more cost-effective and accessible imaging option compared to MRI. Nevertheless, CT exhibits inferior soft-tissue contrast and higher noise levels, yielding less precise structural clarity. In response, leveraging more readily available CT to construct its counterpart MRI, namely, medical image-to-image translation (I2I), serves as a promising solution. Particularly, while diffusion models (DMs) have recently risen as a powerhouse, they also come with a few practical caveats for medical I2I. First, DMs' inherent stochasticity from random noise sampling cannot guarantee consistent MRI generation that faithfully reflects its CT. Second, for 3D volumetric images which are prevalent in medical imaging, naively using 2D DMs leads to slice inconsistency, e.g., abnormal structural and brightness changes. While 3D DMs do exist, significant training costs and data dependency bring hesitation. As a solution, we propose novel style key conditioning (SKC) and inter-slice trajectory alignment (ISTA) sampling for the 2D Brownian bridge diffusion model. Specifically, SKC ensures a consistent imaging style (e.g., contrast) across slices, and ISTA interconnects the independent sampling of each slice, deterministically achieving style and shape consistent 3D CT-to-MRI translation. To the best of our knowledge, this study is the first to achieve high-quality 3D medical I2I based only on a 2D DM with no extra architectural models. Our experimental results show superior 3D medical I2I than existing 2D and 3D baselines, using in-house CT-MRI dataset and BraTS2023 FLAIR-T1 MRI dataset.

FALCON: Frequency Adjoint Link with CONtinuous Density Mask for Fast Single Image Dehazing

Image dehazing, addressing atmospheric interference like fog and haze, remains a pervasive challenge crucial for robust vision applications such as surveillance and remote sensing under adverse visibility. While various methodologies have evolved from early works predicting transmission matrix and atmospheric light features to deep learning and dehazing networks, they innately prioritize dehazing quality metrics, neglecting the need for real-time applicability in time-sensitive domains like autonomous driving. This work introduces FALCON (Frequency Adjoint Link with CONtinuous density mask), a single-image dehazing system achieving state-of-the-art performance on both quality and speed. Particularly, we develop a novel bottleneck module, namely, Frequency Adjoint Link, operating in the frequency space to globally expand the receptive field with minimal growth in network size. Further, we leverage the underlying haze distribution based on the atmospheric scattering model via a Continuous Density Mask (CDM) which serves as a continuous-valued mask input prior and a differentiable auxiliary loss. Comprehensive experiments involving multiple state-of-the-art methods and ablation analysis demonstrate FALCON's exceptional performance in both dehazing quality and speed (i.e., >$180 frames-per-second), quantified by metrics such as FPS, PSNR, and SSIM.

WoLF: Wide-scope Large Language Model Framework for CXR Understanding

Significant methodological strides have been made toward Chest X-ray (CXR) understanding via modern vision-language models (VLMs), demonstrating impressive Visual Question Answering (VQA) and CXR report generation abilities. However, existing CXR understanding frameworks still possess several procedural caveats. (1) Previous methods solely use CXR reports, which are insufficient for comprehensive Visual Question Answering (VQA), especially when additional health-related data like medication history and prior diagnoses are needed. (2) Previous methods use raw CXR reports, which are often arbitrarily structured. While modern language models can understand various text formats, restructuring reports for clearer, organized anatomy-based information could enhance their usefulness. (3) Current evaluation methods for CXR-VQA primarily emphasize linguistic correctness, lacking the capability to offer nuanced assessments of the generated answers. In this work, to address the aforementioned caveats, we introduce WoLF, a Wide-scope Large Language Model Framework for CXR understanding. To resolve (1), we capture multi-faceted records of patients, which are utilized for accurate diagnoses in real-world clinical scenarios. Specifically, we adopt the Electronic Health Records (EHR) to generate instruction-following data suited for CXR understanding. Regarding (2), we enhance report generation performance by decoupling knowledge in CXR reports based on anatomical structure even within the attention step via masked attention. To address (3), we introduce an AI-evaluation protocol optimized for assessing the capabilities of LLM. Through extensive experimental validations, WoLF demonstrates superior performance over other models on MIMIC-CXR in the AI-evaluation arena about VQA (up to +9.47%p mean score) and by metrics about report generation (+7.3%p BLEU-1).

Advancing Text-Driven Chest X-Ray Generation with Policy-Based Reinforcement Learning

Recent advances in text-conditioned image generation diffusion models have begun paving the way for new opportunities in modern medical domain, in particular, generating Chest X-rays (CXRs) from diagnostic reports. Nonetheless, to further drive the diffusion models to generate CXRs that faithfully reflect the complexity and diversity of real data, it has become evident that a nontrivial learning approach is needed. In light of this, we propose CXRL, a framework motivated by the potential of reinforcement learning (RL). Specifically, we integrate a policy gradient RL approach with well-designed multiple distinctive CXR-domain specific reward models. This approach guides the diffusion denoising trajectory, achieving precise CXR posture and pathological details. Here, considering the complex medical image environment, we present "RL with Comparative Feedback" (RLCF) for the reward mechanism, a human-like comparative evaluation that is known to be more effective and reliable in complex scenarios compared to direct evaluation. Our CXRL framework includes jointly optimizing learnable adaptive condition embeddings (ACE) and the image generator, enabling the model to produce more accurate and higher perceptual CXR quality. Our extensive evaluation of the MIMIC-CXR-JPG dataset demonstrates the effectiveness of our RL-based tuning approach. Consequently, our CXRL generates pathologically realistic CXRs, establishing a new standard for generating CXRs with high fidelity to real-world clinical scenarios.

EAGLE: Eigen Aggregation Learning for Object-Centric Unsupervised Semantic Segmentation

Semantic segmentation has innately relied on extensive pixel-level labeled annotated data, leading to the emergence of unsupervised methodologies. Among them, leveraging self-supervised Vision Transformers for unsupervised semantic segmentation (USS) has been making steady progress with expressive deep features. Yet, for semantically segmenting images with complex objects, a predominant challenge remains: the lack of explicit object-level semantic encoding in patch-level features. This technical limitation often leads to inadequate segmentation of complex objects with diverse structures. To address this gap, we present a novel approach, EAGLE, which emphasizes object-centric representation learning for unsupervised semantic segmentation. Specifically, we introduce EiCue, a spectral technique providing semantic and structural cues through an eigenbasis derived from the semantic similarity matrix of deep image features and color affinity from an image. Further, by incorporating our object-centric contrastive loss with EiCue, we guide our model to learn object-level representations with intra- and inter-image object-feature consistency, thereby enhancing semantic accuracy. Extensive experiments on COCO-Stuff, Cityscapes, and Potsdam-3 datasets demonstrate the state-of-the-art USS results of EAGLE with accurate and consistent semantic segmentation across complex scenes.

Evidence-empowered Transfer Learning for Alzheimer's Disease

Transfer learning has been widely utilized to mitigate the data scarcity problem in the field of Alzheimer's disease (AD). Conventional transfer learning relies on re-using models trained on AD-irrelevant tasks such as natural image classification. However, it often leads to negative transfer due to the discrepancy between the non-medical source and target medical domains. To address this, we present evidence-empowered transfer learning for AD diagnosis. Unlike conventional approaches, we leverage an AD-relevant auxiliary task, namely morphological change prediction, without requiring additional MRI data. In this auxiliary task, the diagnosis model learns the evidential and transferable knowledge from morphological features in MRI scans. Experimental results demonstrate that our framework is not only effective in improving detection performance regardless of model capacity, but also more data-efficient and faithful.