Learning Massive-scale Partial Correlation Networks in Clinical Multi-omics Studies with HP-ACCORD

Graphical model estimation from modern multi-omics data requires a balance between statistical estimation performance and computational scalability. We introduce a novel pseudolikelihood-based graphical model framework that reparameterizes the target precision matrix while preserving sparsity pattern and estimates it by minimizing an $\ell_1$-penalized empirical risk based on a new loss function. The proposed estimator maintains estimation and selection consistency in various metrics under high-dimensional assumptions. The associated optimization problem allows for a provably fast computation algorithm using a novel operator-splitting approach and communication-avoiding distributed matrix multiplication. A high-performance computing implementation of our framework was tested in simulated data with up to one million variables demonstrating complex dependency structures akin to biological networks. Leveraging this scalability, we estimated partial correlation network from a dual-omic liver cancer data set. The co-expression network estimated from the ultrahigh-dimensional data showed superior specificity in prioritizing key transcription factors and co-activators by excluding the impact of epigenomic regulation, demonstrating the value of computational scalability in multi-omic data analysis. %derived from the gene expression data.

Feature Augmentation based Test-Time Adaptation

Test-time adaptation (TTA) allows a model to be adapted to an unseen domain without accessing the source data. Due to the nature of practical environments, TTA has a limited amount of data for adaptation. Recent TTA methods further restrict this by filtering input data for reliability, making the effective data size even smaller and limiting adaptation potential. To address this issue, We propose Feature Augmentation based Test-time Adaptation (FATA), a simple method that fully utilizes the limited amount of input data through feature augmentation. FATA employs Normalization Perturbation to augment features and adapts the model using the FATA loss, which makes the outputs of the augmented and original features similar. FATA is model-agnostic and can be seamlessly integrated into existing models without altering the model architecture. We demonstrate the effectiveness of FATA on various models and scenarios on ImageNet-C and Office-Home, validating its superiority in diverse real-world conditions.

Beyond Entropy: Style Transfer Guided Single Image Continual Test-Time Adaptation

Continual test-time adaptation (cTTA) methods are designed to facilitate the continual adaptation of models to dynamically changing real-world environments where computational resources are limited. Due to this inherent limitation, existing approaches fail to simultaneously achieve accuracy and efficiency. In detail, when using a single image, the instability caused by batch normalization layers and entropy loss significantly destabilizes many existing methods in real-world cTTA scenarios. To overcome these challenges, we present BESTTA, a novel single image continual test-time adaptation method guided by style transfer, which enables stable and efficient adaptation to the target environment by transferring the style of the input image to the source style. To implement the proposed method, we devise BeIN, a simple yet powerful normalization method, along with the style-guided losses. We demonstrate that BESTTA effectively adapts to the continually changing target environment, leveraging only a single image on both semantic segmentation and image classification tasks. Remarkably, despite training only two parameters in a BeIN layer consuming the least memory, BESTTA outperforms existing state-of-the-art methods in terms of performance.

DEVIAS: Learning Disentangled Video Representations of Action and Scene for Holistic Video Understanding

When watching a video, humans can naturally extract human actions from the surrounding scene context, even when action-scene combinations are unusual. However, unlike humans, video action recognition models often learn scene-biased action representations from the spurious correlation in training data, leading to poor performance in out-of-context scenarios. While scene-debiased models achieve improved performance in out-of-context scenarios, they often overlook valuable scene information in the data. Addressing this challenge, we propose Disentangled VIdeo representations of Action and Scene (DEVIAS), which aims to achieve holistic video understanding. Disentangled action and scene representations with our method could provide flexibility to adjust the emphasis on action or scene information depending on downstream task and dataset characteristics. Disentangled action and scene representations could be beneficial for both in-context and out-of-context video understanding. To this end, we employ slot attention to learn disentangled action and scene representations with a single model, along with auxiliary tasks that further guide slot attention. We validate the proposed method on both in-context datasets: UCF-101 and Kinetics-400, and out-of-context datasets: SCUBA and HAT. Our proposed method shows favorable performance across different datasets compared to the baselines, demonstrating its effectiveness in diverse video understanding scenarios.

MetaWeather: Few-Shot Weather-Degraded Image Restoration via Degradation Pattern Matching

Real-world vision tasks frequently suffer from the appearance of adverse weather conditions including rain, fog, snow, and raindrops in captured images. Recently, several generic methods for restoring weather-degraded images have been proposed, aiming to remove multiple types of adverse weather effects present in the images. However, these methods have considered weather as discrete and mutually exclusive variables, leading to failure in generalizing to unforeseen weather conditions beyond the scope of the training data, such as the co-occurrence of rain, fog, and raindrops. To this end, weather-degraded image restoration models should have flexible adaptability to the current unknown weather condition to ensure reliable and optimal performance. The adaptation method should also be able to cope with data scarcity for real-world adaptation. This paper proposes MetaWeather, a few-shot weather-degraded image restoration method for arbitrary weather conditions. For this, we devise the core piece of MetaWeather, coined Degradation Pattern Matching Module (DPMM), which leverages representations from a few-shot support set by matching features between input and sample images under new weather conditions. In addition, we build meta-knowledge with episodic meta-learning on top of our MetaWeather architecture to provide flexible adaptability. In the meta-testing phase, we adopt a parameter-efficient fine-tuning method to preserve the prebuilt knowledge and avoid the overfitting problem. Experiments on the BID Task II.A dataset show our method achieves the best performance on PSNR and SSIM compared to state-of-the-art image restoration methods. Code is available at (TBA).