Dynamic Multi-Domain Knowledge Networks for Chest X-ray Report Generation

The automated generation of radiology diagnostic reports helps radiologists make timely and accurate diagnostic decisions while also enhancing clinical diagnostic efficiency. However, the significant imbalance in the distribution of data between normal and abnormal samples (including visual and textual biases) poses significant challenges for a data-driven task like automatically generating diagnostic radiology reports. Therefore, we propose a Dynamic Multi-Domain Knowledge(DMDK) network for radiology diagnostic report generation. The DMDK network consists of four modules: Chest Feature Extractor(CFE), Dynamic Knowledge Extractor(DKE), Specific Knowledge Extractor(SKE), and Multi-knowledge Integrator(MKI) module. Specifically, the CFE module is primarily responsible for extracting the unprocessed visual medical features of the images. The DKE module is responsible for extracting dynamic disease topic labels from the retrieved radiology diagnostic reports. We then fuse the dynamic disease topic labels with the original visual features of the images to highlight the abnormal regions in the original visual features to alleviate the visual data bias problem. The SKE module expands upon the conventional static knowledge graph to mitigate textual data biases and amplify the interpretability capabilities of the model via domain-specific dynamic knowledge graphs. The MKI distills all the knowledge and generates the final diagnostic radiology report. We performed extensive experiments on two widely used datasets, IU X-Ray and MIMIC-CXR. The experimental results demonstrate the effectiveness of our method, with all evaluation metrics outperforming previous state-of-the-art models.

Cross-domain Robust Deepfake Bias Expansion Network for Face Forgery Detection

The rapid advancement of deepfake technologies raises significant concerns about the security of face recognition systems. While existing methods leverage the clues left by deepfake techniques for face forgery detection, malicious users may intentionally manipulate forged faces to obscure the traces of deepfake clues and thereby deceive detection tools. Meanwhile, attaining cross-domain robustness for data-based methods poses a challenge due to potential gaps in the training data, which may not encompass samples from all relevant domains. Therefore, in this paper, we introduce a solution - a Cross-Domain Robust Bias Expansion Network (BENet) - designed to enhance face forgery detection. BENet employs an auto-encoder to reconstruct input faces, maintaining the invariance of real faces while selectively enhancing the difference between reconstructed fake faces and their original counterparts. This enhanced bias forms a robust foundation upon which dependable forgery detection can be built. To optimize the reconstruction results in BENet, we employ a bias expansion loss infused with contrastive concepts to attain the aforementioned objective. In addition, to further heighten the amplification of forged clues, BENet incorporates a Latent-Space Attention (LSA) module. This LSA module effectively captures variances in latent features between the auto-encoder's encoder and decoder, placing emphasis on inconsistent forgery-related information. Furthermore, BENet incorporates a cross-domain detector with a threshold to determine whether the sample belongs to a known distribution. The correction of classification results through the cross-domain detector enables BENet to defend against unknown deepfake attacks from cross-domain. Extensive experiments demonstrate the superiority of BENet compared with state-of-the-art methods in intra-database and cross-database evaluations.

Occlusion-Aware Deep Convolutional Neural Network via Homogeneous Tanh-transforms for Face Parsing

Face parsing infers a pixel-wise label map for each semantic facial component. Previous methods generally work well for uncovered faces, however overlook the facial occlusion and ignore some contextual area outside a single face, especially when facial occlusion has become a common situation during the COVID-19 epidemic. Inspired by the illumination theory of image, we propose a novel homogeneous tanh-transforms for image preprocessing, which made up of four tanh-transforms, that fuse the central vision and the peripheral vision together. Our proposed method addresses the dilemma of face parsing under occlusion and compresses more information of surrounding context. Based on homogeneous tanh-transforms, we propose an occlusion-aware convolutional neural network for occluded face parsing. It combines the information both in Tanh-polar space and Tanh-Cartesian space, capable of enhancing receptive fields. Furthermore, we introduce an occlusion-aware loss to focus on the boundaries of occluded regions. The network is simple and flexible, and can be trained end-to-end. To facilitate future research of occluded face parsing, we also contribute a new cleaned face parsing dataset, which is manually purified from several academic or industrial datasets, including CelebAMask-HQ, Short-video Face Parsing as well as Helen dataset and will make it public. Experiments demonstrate that our method surpasses state-of-art methods of face parsing under occlusion.

A New Computer-Aided Diagnosis System with Modified Genetic Feature Selection for BI-RADS Classification of Breast Masses in Mammograms

Mammography remains the most prevalent imaging tool for early breast cancer screening. The language used to describe abnormalities in mammographic reports is based on the breast Imaging Reporting and Data System (BI-RADS). Assigning a correct BI-RADS category to each examined mammogram is a strenuous and challenging task for even experts. This paper proposes a new and effective computer-aided diagnosis (CAD) system to classify mammographic masses into four assessment categories in BI-RADS. The mass regions are first enhanced by means of histogram equalization and then semiautomatically segmented based on the region growing technique. A total of 130 handcrafted BI-RADS features are then extrcated from the shape, margin, and density of each mass, together with the mass size and the patient's age, as mentioned in BI-RADS mammography. Then, a modified feature selection method based on the genetic algorithm (GA) is proposed to select the most clinically significant BI-RADS features. Finally, a back-propagation neural network (BPN) is employed for classification, and its accuracy is used as the fitness in GA. A set of 500 mammogram images from the digital database of screening mammography (DDSM) is used for evaluation. Our system achieves classification accuracy, positive predictive value, negative predictive value, and Matthews correlation coefficient of 84.5%, 84.4%, 94.8%, and 79.3%, respectively. To our best knowledge, this is the best current result for BI-RADS classification of breast masses in mammography, which makes the proposed system promising to support radiologists for deciding proper patient management based on the automatically assigned BI-RADS categories.

A New Three-stage Curriculum Learning Approach to Deep Network Based Liver Tumor Segmentation

Automatic segmentation of liver tumors in medical images is crucial for the computer-aided diagnosis and therapy. It is a challenging task, since the tumors are notoriously small against the background voxels. This paper proposes a new three-stage curriculum learning approach for training deep networks to tackle this small object segmentation problem. The learning in the first stage is performed on the whole input to obtain an initial deep network for tumor segmenta-tion. Then the second stage of learning focuses the strength-ening of tumor specific features by continuing training the network on the tumor patches. Finally, we retrain the net-work on the whole input in the third stage, in order that the tumor specific features and the global context can be inte-grated ideally under the segmentation objective. Benefitting from the proposed learning approach, we only need to em-ploy one single network to segment the tumors directly. We evaluated our approach on the 2017 MICCAI Liver Tumor Segmentation challenge dataset. In the experiments, our approach exhibits significant improvement compared with the commonly used cascaded counterpart.