Is SAM 2 Better than SAM in Medical Image Segmentation?

Segment Anything Model (SAM) demonstrated impressive performance in zero-shot promptable segmentation on natural images. The recently released Segment Anything Model 2 (SAM 2) model claims to have better performance than SAM on images while extending the model's capabilities to video segmentation. It is important to evaluate the recent model's ability in medical image segmentation in a zero-shot promptable manner. In this work, we performed extensive studies with multiple datasets from different imaging modalities to compare the performance between SAM and SAM 2. We used two point prompt strategies: (i) single positive prompt near the centroid of the target structure and (ii) additional positive prompts placed randomly within the target structure. The evaluation included 21 unique organ-modality combinations including abdominal structures, cardiac structures, and fetal head images acquired from publicly available MRI, CT, and Ultrasound datasets. The preliminary results, based on 2D images, indicate that while SAM 2 may perform slightly better in a few cases, but it does not in general surpass SAM for medical image segmentation. Especially when the contrast is lower like in CT, Ultrasound images, SAM 2 performs poorly than SAM. For MRI images, SAM 2 performs at par or better than SAM. Similar to SAM, SAM 2 also suffers from over-segmentation issue especially when the boundaries of the to-be-segmented organ is fuzzy in nature.

Adversarial Focal Loss: Asking Your Discriminator for Hard Examples

Focal Loss has reached incredible popularity as it uses a simple technique to identify and utilize hard examples to achieve better performance on classification. However, this method does not easily generalize outside of classification tasks, such as in keypoint detection. In this paper, we propose a novel adaptation of Focal Loss for keypoint detection tasks, called Adversarial Focal Loss (AFL). AFL not only is semantically analogous to Focal loss, but also works as a plug-and-chug upgrade for arbitrary loss functions. While Focal Loss requires output from a classifier, AFL leverages a separate adversarial network to produce a difficulty score for each input. This difficulty score can then be used to dynamically prioritize learning on hard examples, even in absence of a classifier. In this work, we show AFL's effectiveness in enhancing existing methods in keypoint detection and verify its capability to re-weigh examples based on difficulty.

Pristine annotations-based multi-modal trained artificial intelligence solution to triage chest X-ray for COVID-19

The COVID-19 pandemic continues to spread and impact the well-being of the global population. The front-line modalities including computed tomography (CT) and X-ray play an important role for triaging COVID patients. Considering the limited access of resources (both hardware and trained personnel) and decontamination considerations, CT may not be ideal for triaging suspected subjects. Artificial intelligence (AI) assisted X-ray based applications for triaging and monitoring require experienced radiologists to identify COVID patients in a timely manner and to further delineate the disease region boundary are seen as a promising solution. Our proposed solution differs from existing solutions by industry and academic communities, and demonstrates a functional AI model to triage by inferencing using a single x-ray image, while the deep-learning model is trained using both X-ray and CT data. We report on how such a multi-modal training improves the solution compared to X-ray only training. The multi-modal solution increases the AUC (area under the receiver operating characteristic curve) from 0.89 to 0.93 and also positively impacts the Dice coefficient (0.59 to 0.62) for localizing the pathology. To the best our knowledge, it is the first X-ray solution by leveraging multi-modal information for the development.

Transformer Based Language Models for Similar Text Retrieval and Ranking

Most approaches for similar text retrieval and ranking with long natural language queries rely at some level on queries and responses having words in common with each other. Recent applications of transformer-based neural language models to text retrieval and ranking problems have been very promising, but still involve a two-step process in which result candidates are first obtained through bag-of-words-based approaches, and then reranked by a neural transformer. In this paper, we introduce novel approaches for effectively applying neural transformer models to similar text retrieval and ranking without an initial bag-of-words-based step. By eliminating the bag-of-words-based step, our approach is able to accurately retrieve and rank results even when they have no non-stopwords in common with the query. We accomplish this by using bidirectional encoder representations from transformers (BERT) to create vectorized representations of sentence-length texts, along with a vector nearest neighbor search index. We demonstrate both supervised and unsupervised means of using BERT to accomplish this task.