Input Data Adaptive Learning for Sub-acute Ischemic Stroke Lesion Segmentation

In machine learning larger databases are usually associated with higher classification accuracy due to better generalization. This generalization may lead to non-optimal classifiers in some medical applications with highly variable expressions of pathologies. This paper presents a method for learning from a large training base by adaptively selecting optimal training samples for given input data. In this way heterogeneous databases are supported two-fold. First, by being able to deal with sparsely annotated data allows a quick inclusion of new data set and second, by training an input-dependent classifier. The proposed approach is evaluated using the SISS challenge. The proposed algorithm leads to a significant improvement of the classification accuracy.

DALSA: Domain Adaptation for Supervised Learning From Sparsely Annotated MR Images

We propose a new method that employs transfer learning techniques to effectively correct sampling selection errors introduced by sparse annotations during supervised learning for automated tumor segmentation. The practicality of current learning-based automated tissue classification approaches is severely impeded by their dependency on manually segmented training databases that need to be recreated for each scenario of application, site, or acquisition setup. The comprehensive annotation of reference datasets can be highly labor-intensive, complex, and error-prone. The proposed method derives high-quality classifiers for the different tissue classes from sparse and unambiguous annotations and employs domain adaptation techniques for effectively correcting sampling selection errors introduced by the sparse sampling. The new approach is validated on labeled, multi-modal MR images of 19 patients with malignant gliomas and by comparative analysis on the BraTS 2013 challenge data sets. Compared to training on fully labeled data, we reduced the time for labeling and training by a factor greater than 70 and 180 respectively without sacrificing accuracy. This dramatically eases the establishment and constant extension of large annotated databases in various scenarios and imaging setups and thus represents an important step towards practical applicability of learning-based approaches in tissue classification.

Knowledge Graphs as Context Sources for LLM-Based Explanations of Learning Recommendations

In the era of personalized education, the provision of comprehensible explanations for learning recommendations is of a great value to enhance the learner's understanding and engagement with the recommended learning content. Large language models (LLMs) and generative AI in general have recently opened new doors for generating human-like explanations, for and along learning recommendations. However, their precision is still far away from acceptable in a sensitive field like education. To harness the abilities of LLMs, while still ensuring a high level of precision towards the intent of the learners, this paper proposes an approach to utilize knowledge graphs (KG) as a source of factual context, for LLM prompts, reducing the risk of model hallucinations, and safeguarding against wrong or imprecise information, while maintaining an application-intended learning context. We utilize the semantic relations in the knowledge graph to offer curated knowledge about learning recommendations. With domain-experts in the loop, we design the explanation as a textual template, which is filled and completed by the LLM. Domain experts were integrated in the prompt engineering phase as part of a study, to ensure that explanations include information that is relevant to the learner. We evaluate our approach quantitatively using Rouge-N and Rouge-L measures, as well as qualitatively with experts and learners. Our results show an enhanced recall and precision of the generated explanations compared to those generated solely by the GPT model, with a greatly reduced risk of generating imprecise information in the final learning explanation.

Building Contextual Knowledge Graphs for Personalized Learning Recommendations using Text Mining and Semantic Graph Completion

Modelling learning objects (LO) within their context enables the learner to advance from a basic, remembering-level, learning objective to a higher-order one, i.e., a level with an application- and analysis objective. While hierarchical data models are commonly used in digital learning platforms, using graph-based models enables representing the context of LOs in those platforms. This leads to a foundation for personalized recommendations of learning paths. In this paper, the transformation of hierarchical data models into knowledge graph (KG) models of LOs using text mining is introduced and evaluated. We utilize custom text mining pipelines to mine semantic relations between elements of an expert-curated hierarchical model. We evaluate the KG structure and relation extraction using graph quality-control metrics and the comparison of algorithmic semantic-similarities to expert-defined ones. The results show that the relations in the KG are semantically comparable to those defined by domain experts, and that the proposed KG improves representing and linking the contexts of LOs through increasing graph communities and betweenness centrality.

Supporting Student Decisions on Learning Recommendations: An LLM-Based Chatbot with Knowledge Graph Contextualization for Conversational Explainability and Mentoring

Student commitment towards a learning recommendation is not separable from their understanding of the reasons it was recommended to them; and their ability to modify it based on that understanding. Among explainability approaches, chatbots offer the potential to engage the student in a conversation, similar to a discussion with a peer or a mentor. The capabilities of chatbots, however, are still not sufficient to replace a human mentor, despite the advancements of generative AI (GenAI) and large language models (LLM). Therefore, we propose an approach to utilize chatbots as mediators of the conversation and sources of limited and controlled generation of explanations, to harvest the potential of LLMs while reducing their potential risks at the same time. The proposed LLM-based chatbot supports students in understanding learning-paths recommendations. We use a knowledge graph (KG) as a human-curated source of information, to regulate the LLM's output through defining its prompt's context. A group chat approach is developed to connect students with human mentors, either on demand or in cases that exceed the chatbot's pre-defined tasks. We evaluate the chatbot with a user study, to provide a proof-of-concept and highlight the potential requirements and limitations of utilizing chatbots in conversational explainability.

Explainable Graph-based Search for Lessons-Learned Documents in the Semiconductor Industry

Industrial processes produce a considerable volume of data and thus information. Whether it is structured sensory data or semi- to unstructured textual data, the knowledge that can be derived from it is critical to the sustainable development of the industrial process. A key challenge of this sustainability is the intelligent management of the generated data, as well as the knowledge extracted from it, in order to utilize this knowledge for improving future procedures. This challenge is a result of the tailored documentation methods and domain-specific requirements, which include the need for quick visibility of the documented knowledge. In this paper, we utilize the expert knowledge documented in chip-design failure reports in supporting user access to information that is relevant to a current chip design. Unstructured, free, textual data in previous failure documentations provides a valuable source of lessons-learned, which expert design-engineers have experienced, solved and documented. To achieve a sustainable utilization of knowledge within the company, not only the inherent knowledge has to be mined from unstructured textual data, but also the relations between the lessons-learned, uncovering potentially unknown links. In this research, a knowledge graph is constructed, in order to represent and use the interconnections between reported design failures. A search engine is developed and applied onto the graph to answer queries. In contrast to mere keyword-based searching, the searchability of the knowledge graph offers enhanced search results beyond direct matches and acts as a mean for generating explainable results and result recommendations. Results are provided to the design engineer through an interactive search interface, in which, the feedback from the user is used to further optimize relations for future iterations of the knowledge graph.