MALLOC: Benchmarking the Memory-aware Long Sequence Compression for Large Sequential Recommendation

The scaling law, which indicates that model performance improves with increasing dataset and model capacity, has fueled a growing trend in expanding recommendation models in both industry and academia. However, the advent of large-scale recommenders also brings significantly higher computational costs, particularly under the long-sequence dependencies inherent in the user intent of recommendation systems. Current approaches often rely on pre-storing the intermediate states of the past behavior for each user, thereby reducing the quadratic re-computation cost for the following requests. Despite their effectiveness, these methods often treat memory merely as a medium for acceleration, without adequately considering the space overhead it introduces. This presents a critical challenge in real-world recommendation systems with billions of users, each of whom might initiate thousands of interactions and require massive memory for state storage. Fortunately, there have been several memory management strategies examined for compression in LLM, while most have not been evaluated on the recommendation task. To mitigate this gap, we introduce MALLOC, a comprehensive benchmark for memory-aware long sequence compression. MALLOC presents a comprehensive investigation and systematic classification of memory management techniques applicable to large sequential recommendations. These techniques are integrated into state-of-the-art recommenders, enabling a reproducible and accessible evaluation platform. Through extensive experiments across accuracy, efficiency, and complexity, we demonstrate the holistic reliability of MALLOC in advancing large-scale recommendation. Code is available at https://anonymous.4open.science/r/MALLOC.

Enabling Collaborative Clinical Diagnosis of Infectious Keratitis by Integrating Expert Knowledge and Interpretable Data-driven Intelligence

Although data-driven artificial intelligence (AI) in medical image diagnosis has shown impressive performance in silico, the lack of interpretability makes it difficult to incorporate the "black box" into clinicians' workflows. To make the diagnostic patterns learned from data understandable by clinicians, we develop an interpretable model, knowledge-guided diagnosis model (KGDM), that provides a visualized reasoning process containing AI-based biomarkers and retrieved cases that with the same diagnostic patterns. It embraces clinicians' prompts into the interpreted reasoning through human-AI interaction, leading to potentially enhanced safety and more accurate predictions. This study investigates the performance, interpretability, and clinical utility of KGDM in the diagnosis of infectious keratitis (IK), which is the leading cause of corneal blindness. The classification performance of KGDM is evaluated on a prospective validation dataset, an external testing dataset, and an publicly available testing dataset. The diagnostic odds ratios (DOR) of the interpreted AI-based biomarkers are effective, ranging from 3.011 to 35.233 and exhibit consistent diagnostic patterns with clinic experience. Moreover, a human-AI collaborative diagnosis test is conducted and the participants with collaboration achieved a performance exceeding that of both humans and AI. By synergistically integrating interpretability and interaction, this study facilitates the convergence of clinicians' expertise and data-driven intelligence. The promotion of inexperienced ophthalmologists with the aid of AI-based biomarkers, as well as increased AI prediction by intervention from experienced ones, demonstrate a promising diagnostic paradigm for infectious keratitis using KGDM, which holds the potential for extension to other diseases where experienced medical practitioners are limited and the safety of AI is concerned.