HyperWalker: Dynamic Hypergraph-Based Deep Diagnosis for Multi-Hop Clinical Modeling across EHR and X-Ray in Medical VLMs

Automated clinical diagnosis remains a core challenge in medical AI, which usually requires models to integrate multi-modal data and reason across complex, case-specific contexts. Although recent methods have advanced medical report generation (MRG) and visual question answering (VQA) with medical vision-language models (VLMs), these methods, however, predominantly operate under a sample-isolated inference paradigm, as such processing cases independently without access to longitudinal electronic health records (EHRs) or structurally related patient examples. This paradigm limits reasoning to image-derived information alone, which ignores external complementary medical evidence for potentially more accurate diagnosis. To overcome this limitation, we propose \textbf{HyperWalker}, a \textit{Deep Diagnosis} framework that reformulates clinical reasoning via dynamic hypergraphs and test-time training. First, we construct a dynamic hypergraph, termed \textbf{iBrochure}, to model the structural heterogeneity of EHR data and implicit high-order associations among multimodal clinical information. Within this hypergraph, a reinforcement learning agent, \textbf{Walker}, navigates to and identifies optimal diagnostic paths. To ensure comprehensive coverage of diverse clinical characteristics in test samples, we incorporate a \textit{linger mechanism}, a multi-hop orthogonal retrieval strategy that iteratively selects clinically complementary neighborhood cases reflecting distinct clinical attributes. Experiments on MRG with MIMIC and medical VQA on EHRXQA demonstrate that HyperWalker achieves state-of-the-art performance. Code is available at: https://github.com/Bean-Young/HyperWalker

UltraGS: Gaussian Splatting for Ultrasound Novel View Synthesis

Ultrasound imaging is a cornerstone of non-invasive clinical diagnostics, yet its limited field of view complicates novel view synthesis. We propose \textbf{UltraGS}, a Gaussian Splatting framework optimized for ultrasound imaging. First, we introduce a depth-aware Gaussian splatting strategy, where each Gaussian is assigned a learnable field of view, enabling accurate depth prediction and precise structural representation. Second, we design SH-DARS, a lightweight rendering function combining low-order spherical harmonics with ultrasound-specific wave physics, including depth attenuation, reflection, and scattering, to model tissue intensity accurately. Third, we contribute the Clinical Ultrasound Examination Dataset, a benchmark capturing diverse anatomical scans under real-world clinical protocols. Extensive experiments on three datasets demonstrate UltraGS's superiority, achieving state-of-the-art results in PSNR (up to 29.55), SSIM (up to 0.89), and MSE (as low as 0.002) while enabling real-time synthesis at 64.69 fps. The code and dataset are open-sourced at: https://github.com/Bean-Young/UltraGS.

Auto-US: An Ultrasound Video Diagnosis Agent Using Video Classification Framework and LLMs

AI-assisted ultrasound video diagnosis presents new opportunities to enhance the efficiency and accuracy of medical imaging analysis. However, existing research remains limited in terms of dataset diversity, diagnostic performance, and clinical applicability. In this study, we propose \textbf{Auto-US}, an intelligent diagnosis agent that integrates ultrasound video data with clinical diagnostic text. To support this, we constructed \textbf{CUV Dataset} of 495 ultrasound videos spanning five categories and three organs, aggregated from multiple open-access sources. We developed \textbf{CTU-Net}, which achieves state-of-the-art performance in ultrasound video classification, reaching an accuracy of 86.73\% Furthermore, by incorporating large language models, Auto-US is capable of generating clinically meaningful diagnostic suggestions. The final diagnostic scores for each case exceeded 3 out of 5 and were validated by professional clinicians. These results demonstrate the effectiveness and clinical potential of Auto-US in real-world ultrasound applications. Code and data are available at: https://github.com/Bean-Young/Auto-US.

Explicit and Implicit Representations in AI-based 3D Reconstruction for Radiology: A systematic literature review

The demand for high-quality medical imaging in clinical practice and assisted diagnosis has made 3D reconstruction in radiological imaging a key research focus. Artificial intelligence (AI) has emerged as a promising approach to enhancing reconstruction accuracy while reducing acquisition and processing time, thereby minimizing patient radiation exposure and discomfort and ultimately benefiting clinical diagnosis. This review explores state-of-the-art AI-based 3D reconstruction algorithms in radiological imaging, categorizing them into explicit and implicit approaches based on their underlying principles. Explicit methods include point-based, volume-based, and Gaussian representations, while implicit methods encompass implicit prior embedding and neural radiance fields. Additionally, we examine commonly used evaluation metrics and benchmark datasets. Finally, we discuss the current state of development, key challenges, and future research directions in this evolving field. Our project available on: https://github.com/Bean-Young/AI4Med.