End-to-end Multi-source Visual Prompt Tuning for Survival Analysis in Whole Slide Images

Survival analysis using pathology images poses a considerable challenge, as it requires the localization of relevant information from the multitude of tiles within whole slide images (WSIs). Current methods typically resort to a two-stage approach, where a pre-trained network extracts features from tiles, which are then used by survival models. This process, however, does not optimize the survival models in an end-to-end manner, and the pre-extracted features may not be ideally suited for survival prediction. To address this limitation, we present a novel end-to-end Visual Prompt Tuning framework for survival analysis, named VPTSurv. VPTSurv refines feature embeddings through an efficient encoder-decoder framework. The encoder remains fixed while the framework introduces tunable visual prompts and adaptors, thus permitting end-to-end training specifically for survival prediction by optimizing only the lightweight adaptors and the decoder. Moreover, the versatile VPTSurv framework accommodates multi-source information as prompts, thereby enriching the survival model. VPTSurv achieves substantial increases of 8.7% and 12.5% in the C-index on two immunohistochemical pathology image datasets. These significant improvements highlight the transformative potential of the end-to-end VPT framework over traditional two-stage methods.

DIVESPOT: Depth Integrated Volume Estimation of Pile of Things Based on Point Cloud

Non-contact volume estimation of pile-type objects has considerable potential in industrial scenarios, including grain, coal, mining, and stone materials. However, using existing method for these scenarios is challenged by unstable measurement poses, significant light interference, the difficulty of training data collection, and the computational burden brought by large piles. To address the above issues, we propose the Depth Integrated Volume EStimation of Pile Of Things (DIVESPOT) based on point cloud technology in this study. For the challenges of unstable measurement poses, the point cloud pose correction and filtering algorithm is designed based on the Random Sample Consensus (RANSAC) and the Hierarchical Density-Based Spatial Clustering of Applications with Noise (HDBSCAN). To cope with light interference and to avoid the relying on training data, the height-distribution-based ground feature extraction algorithm is proposed to achieve RGB-independent. To reduce the computational burden, the storage space optimizing strategy is developed, such that accurate estimation can be acquired by using compressed voxels. Experimental results demonstrate that the DIVESPOT method enables non-data-driven, RGB-independent segmentation of pile point clouds, maintaining a volume calculation relative error within 2%. Even with 90% compression of the voxel mesh, the average error of the results can be under 3%.

Zero3D: Semantic-Driven Multi-Category 3D Shape Generation

Semantic-driven 3D shape generation aims to generate 3D objects conditioned on text. Previous works face problems with single-category generation, low-frequency 3D details, and requiring a large number of paired datasets for training. To tackle these challenges, we propose a multi-category conditional diffusion model. Specifically, 1) to alleviate the problem of lack of large-scale paired data, we bridge the text, 2D image and 3D shape based on the pre-trained CLIP model, and 2) to obtain the multi-category 3D shape feature, we apply the conditional flow model to generate 3D shape vector conditioned on CLIP embedding. 3) to generate multi-category 3D shape, we employ the hidden-layer diffusion model conditioned on the multi-category shape vector, which greatly reduces the training time and memory consumption.