What Drives Length of Stay After Elective Spine Surgery? Insights from a Decade of Predictive Modeling

Objective: Predicting length of stay after elective spine surgery is essential for optimizing patient outcomes and hospital resource use. This systematic review synthesizes computational methods used to predict length of stay in this patient population, highlighting model performance and key predictors. Methods: Following PRISMA guidelines, we systematically searched PubMed, Google Scholar, and ACM Digital Library for studies published between December 1st, 2015, and December 1st, 2024. Eligible studies applied statistical or machine learning models to predict length of stay for elective spine surgery patients. Three reviewers independently screened studies and extracted data. Results: Out of 1,263 screened studies, 29 studies met inclusion criteria. Length of stay was predicted as a continuous, binary, or percentile-based outcome. Models included logistic regression, random forest, boosting algorithms, and neural networks. Machine learning models consistently outperformed traditional statistical models, with AUCs ranging from 0.94 to 0.99. K-Nearest Neighbors and Naive Bayes achieved top performance in some studies. Common predictors included age, comorbidities (notably hypertension and diabetes), BMI, type and duration of surgery, and number of spinal levels. However, external validation and reporting practices varied widely across studies. Discussion: There is growing interest in artificial intelligence and machine learning in length of stay prediction, but lack of standardization and external validation limits clinical utility. Future studies should prioritize standardized outcome definitions and transparent reporting needed to advance real-world deployment. Conclusion: Machine learning models offer strong potential for length of stay prediction after elective spine surgery, highlighting their potential for improving discharge planning and hospital resource management.

YouTube Video Analytics for Patient Engagement: Evidence from Colonoscopy Preparation Videos

Videos can be an effective way to deliver contextualized, just-in-time medical information for patient education. However, video analysis, from topic identification and retrieval to extraction and analysis of medical information and understandability from a patient perspective are extremely challenging tasks. This study demonstrates a data analysis pipeline that utilizes methods to retrieve medical information from YouTube videos on preparing for a colonoscopy exam, a much maligned and disliked procedure that patients find challenging to get adequately prepared for. We first use the YouTube Data API to collect metadata of desired videos on select search keywords and use Google Video Intelligence API to analyze texts, frames and objects data. Then we annotate the YouTube video materials on medical information, video understandability and overall recommendation. We develop a bidirectional long short-term memory (BiLSTM) model to identify medical terms in videos and build three classifiers to group videos based on the levels of encoded medical information and video understandability, and whether the videos are recommended or not. Our study provides healthcare stakeholders with guidelines and a scalable approach for generating new educational video content to enhance management of a vast number of health conditions.

Large Language Models for Disease Diagnosis: A Scoping Review

Automatic disease diagnosis has become increasingly valuable in clinical practice. The advent of large language models (LLMs) has catalyzed a paradigm shift in artificial intelligence, with growing evidence supporting the efficacy of LLMs in diagnostic tasks. Despite the growing attention in this field, many critical research questions remain under-explored. For instance, what diseases and LLM techniques have been investigated for diagnostic tasks? How can suitable LLM techniques and evaluation methods be selected for clinical decision-making? To answer these questions, we performed a comprehensive analysis of LLM-based methods for disease diagnosis. This scoping review examined the types of diseases, associated organ systems, relevant clinical data, LLM techniques, and evaluation methods reported in existing studies. Furthermore, we offered guidelines for data preprocessing and the selection of appropriate LLM techniques and evaluation strategies for diagnostic tasks. We also assessed the limitations of current research and delineated the challenges and future directions in this research field. In summary, our review outlined a blueprint for LLM-based disease diagnosis, helping to streamline and guide future research endeavors.