Artificial Liver Classifier: A New Alternative to Conventional Machine Learning Models

Supervised machine learning classifiers often encounter challenges related to performance, accuracy, and overfitting. This paper introduces the Artificial Liver Classifier (ALC), a novel supervised learning classifier inspired by the human liver's detoxification function. The ALC is characterized by its simplicity, speed, hyperparameters-free, ability to reduce overfitting, and effectiveness in addressing multi-classification problems through straightforward mathematical operations. To optimize the ALC's parameters, an improved FOX optimization algorithm (IFOX) is employed as the training method. The proposed ALC was evaluated on five benchmark machine learning datasets: Iris Flower, Breast Cancer Wisconsin, Wine, Voice Gender, and MNIST. The results demonstrated competitive performance, with the ALC achieving 100% accuracy on the Iris dataset, surpassing logistic regression, multilayer perceptron, and support vector machine. Similarly, on the Breast Cancer dataset, it achieved 99.12% accuracy, outperforming XGBoost and logistic regression. Across all datasets, the ALC consistently exhibited lower overfitting gaps and loss compared to conventional classifiers. These findings highlight the potential of leveraging biological process simulations to develop efficient machine learning models and open new avenues for innovation in the field.

Foxtsage vs. Adam: Revolution or Evolution in Optimization?

Optimization techniques are pivotal in neural network training, shaping both predictive performance and convergence efficiency. This study introduces Foxtsage, a novel hybrid optimisation approach that integrates the Hybrid FOX-TSA with Stochastic Gradient Descent for training Multi-Layer Perceptron models. The proposed Foxtsage method is benchmarked against the widely adopted Adam optimizer across multiple standard datasets, focusing on key performance metrics such as training loss, accuracy, precision, recall, F1-score, and computational time. Experimental results demonstrate that Foxtsage achieves a 42.03% reduction in loss mean (Foxtsage: 9.508, Adam: 16.402) and a 42.19% improvement in loss standard deviation (Foxtsage: 20.86, Adam: 36.085), reflecting enhanced consistency and robustness. Modest improvements in accuracy mean (0.78%), precision mean (0.91%), recall mean (1.02%), and F1-score mean (0.89%) further underscore its predictive performance. However, these gains are accompanied by an increased computational cost, with a 330.87% rise in time mean (Foxtsage: 39.541 seconds, Adam: 9.177 seconds). By effectively combining the global search capabilities of FOX-TSA with the stability and adaptability of SGD, Foxtsage presents itself as a robust and viable alternative for neural network optimization tasks.

NER- RoBERTa: Fine-Tuning RoBERTa for Named Entity Recognition (NER) within low-resource languages

Nowadays, Natural Language Processing (NLP) is an important tool for most people's daily life routines, ranging from understanding speech, translation, named entity recognition (NER), and text categorization, to generative text models such as ChatGPT. Due to the existence of big data and consequently large corpora for widely used languages like English, Spanish, Turkish, Persian, and many more, these applications have been developed accurately. However, the Kurdish language still requires more corpora and large datasets to be included in NLP applications. This is because Kurdish has a rich linguistic structure, varied dialects, and a limited dataset, which poses unique challenges for Kurdish NLP (KNLP) application development. While several studies have been conducted in KNLP for various applications, Kurdish NER (KNER) remains a challenge for many KNLP tasks, including text analysis and classification. In this work, we address this limitation by proposing a methodology for fine-tuning the pre-trained RoBERTa model for KNER. To this end, we first create a Kurdish corpus, followed by designing a modified model architecture and implementing the training procedures. To evaluate the trained model, a set of experiments is conducted to demonstrate the performance of the KNER model using different tokenization methods and trained models. The experimental results show that fine-tuned RoBERTa with the SentencePiece tokenization method substantially improves KNER performance, achieving a 12.8% improvement in F1-score compared to traditional models, and consequently establishes a new benchmark for KNLP.

Decoding Drug Discovery: Exploring A-to-Z In silico Methods for Beginners

The drug development process is a critical challenge in the pharmaceutical industry due to its time-consuming nature and the need to discover new drug potentials to address various ailments. The initial step in drug development, drug target identification, often consumes considerable time. While valid, traditional methods such as in vivo and in vitro approaches are limited in their ability to analyze vast amounts of data efficiently, leading to wasteful outcomes. To expedite and streamline drug development, an increasing reliance on computer-aided drug design (CADD) approaches has merged. These sophisticated in silico methods offer a promising avenue for efficiently identifying viable drug candidates, thus providing pharmaceutical firms with significant opportunities to uncover new prospective drug targets. The main goal of this work is to review in silico methods used in the drug development process with a focus on identifying therapeutic targets linked to specific diseases at the genetic or protein level. This article thoroughly discusses A-to-Z in silico techniques, which are essential for identifying the targets of bioactive compounds and their potential therapeutic effects. This review intends to improve drug discovery processes by illuminating the state of these cutting-edge approaches, thereby maximizing the effectiveness and duration of clinical trials for novel drug target investigation.

Central Kurdish Text-to-Speech Synthesis with Novel End-to-End Transformer Training

Recent advancements in text-to-speech (TTS) models have aimed to streamline the two-stage process into a single-stage training approach. However, many single-stage models still lag behind in audio quality, particularly when handling Kurdish text and speech. There is a critical need to enhance text-to-speech conversion for the Kurdish language, particularly for the Sorani dialect, which has been relatively neglected and is underrepresented in recent text-to-speech advancements. This study introduces an end-to-end TTS model for efficiently generating high-quality Kurdish audio. The proposed method leverages a variational autoencoder (VAE) that is pre-trained for audio waveform reconstruction and is augmented by adversarial training. This involves aligning the prior distribution established by the pre-trained encoder with the posterior distribution of the text encoder within latent variables. Additionally, a stochastic duration predictor is incorporated to imbue synthesized Kurdish speech with diverse rhythms. By aligning latent distributions and integrating the stochastic duration predictor, the proposed method facilitates the real-time generation of natural Kurdish speech audio, offering flexibility in pitches and rhythms. Empirical evaluation via the mean opinion score (MOS) on a custom dataset confirms the superior performance of our approach (MOS of 3.94) compared with that of a one-stage system and other two-staged systems as assessed through a subjective human evaluation.

From A-to-Z Review of Clustering Validation Indices

Data clustering involves identifying latent similarities within a dataset and organizing them into clusters or groups. The outcomes of various clustering algorithms differ as they are susceptible to the intrinsic characteristics of the original dataset, including noise and dimensionality. The effectiveness of such clustering procedures directly impacts the homogeneity of clusters, underscoring the significance of evaluating algorithmic outcomes. Consequently, the assessment of clustering quality presents a significant and complex endeavor. A pivotal aspect affecting clustering validation is the cluster validity metric, which aids in determining the optimal number of clusters. The main goal of this study is to comprehensively review and explain the mathematical operation of internal and external cluster validity indices, but not all, to categorize these indices and to brainstorm suggestions for future advancement of clustering validation research. In addition, we review and evaluate the performance of internal and external clustering validation indices on the most common clustering algorithms, such as the evolutionary clustering algorithm star (ECA*). Finally, we suggest a classification framework for examining the functionality of both internal and external clustering validation measures regarding their ideal values, user-friendliness, responsiveness to input data, and appropriateness across various fields. This classification aids researchers in selecting the appropriate clustering validation measure to suit their specific requirements.

In Search of Excellence: SHOA as a Competitive Shrike Optimization Algorithm for Multimodal Problems

In this paper, a swarm intelligence optimization algorithm is proposed as the Shrike Optimization Algorithm (SHOA). Many creatures living in a group and surviving for the next generation randomly search for food; they follow the best one in the swarm, called swarm intelligence. Swarm-based algorithms are designed to mimic creatures' behaviours, but in multimodal problem competition, they cannot find optimal solutions in some difficult cases. The main inspiration for the proposed algorithm is taken from the swarming behaviours of shrike birds in nature. The shrike birds are migrating from their territory to survive. However, the SHOA mimics the surviving behaviour of shrike birds for living, adaptation, and breeding. Two parts of optimization exploration and exploitation are designed by modelling shrike breeding and searching for foods to feed nestlings until they get ready to fly and live independently. This paper is a mathematical model for the SHOA to perform optimization. The SHOA benchmarked 19 well-known mathematical test functions, 10 from CEC-2019, and 12 from CEC-2022 most recent test functions, a total of 41 competitive mathematical test functions benchmarked and four real-world engineering problems with different conditions, both constrained and unconstrained. The statistical results obtained from the Wilcoxon sum ranking and Fridman test show that SHOA has a significant statistical superiority in handling the test benchmarks compared to competitor algorithms in multi-modal problems. The results for engineering optimization problems show the SHOA outperforms other nature-inspired algorithms in many cases.

FOXANN: A Method for Boosting Neural Network Performance

Artificial neural networks play a crucial role in machine learning and there is a need to improve their performance. This paper presents FOXANN, a novel classification model that combines the recently developed Fox optimizer with ANN to solve ML problems. Fox optimizer replaces the backpropagation algorithm in ANN; optimizes synaptic weights; and achieves high classification accuracy with a minimum loss, improved model generalization, and interpretability. The performance of FOXANN is evaluated on three standard datasets: Iris Flower, Breast Cancer Wisconsin, and Wine. The results presented in this paper are derived from 100 epochs using 10-fold cross-validation, ensuring that all dataset samples are involved in both the training and validation stages. Moreover, the results show that FOXANN outperforms traditional ANN and logistic regression methods as well as other models proposed in the literature such as ABC-ANN, ABC-MNN, CROANN, and PSO-DNN, achieving a higher accuracy of 0.9969 and a lower validation loss of 0.0028. These results demonstrate that FOXANN is more effective than traditional methods and other proposed models across standard datasets. Thus, FOXANN effectively addresses the challenges in ML algorithms and improves classification performance.

Q-FOX Learning: Breaking Tradition in Reinforcement Learning

Reinforcement learning (RL) is a subset of artificial intelligence (AI) where agents learn the best action by interacting with the environment, making it suitable for tasks that do not require labeled data or direct supervision. Hyperparameters (HP) tuning refers to choosing the best parameter that leads to optimal solutions in RL algorithms. Manual or random tuning of the HP may be a crucial process because variations in this parameter lead to changes in the overall learning aspects and different rewards. In this paper, a novel and automatic HP-tuning method called Q-FOX is proposed. This uses both the FOX optimizer, a new optimization method inspired by nature that mimics red foxes' hunting behavior, and the commonly used, easy-to-implement RL Q-learning algorithm to solve the problem of HP tuning. Moreover, a new objective function is proposed which prioritizes the reward over the mean squared error (MSE) and learning time (steps). Q-FOX has been evaluated on two OpenAI Gym environment control tasks: Cart Pole and Frozen Lake. It exposed greater cumulative rewards than HP tuning with other optimizers, such as PSO, GA, Bee, or randomly selected HP. The cumulative reward for the Cart Pole task was 32.08, and for the Frozen Lake task was 0.95. Despite the robustness of Q-FOX, it has limitations. It cannot be used directly in real-word problems before choosing the HP in a simulation environment because its processes work iteratively, making it time-consuming. The results indicate that Q-FOX has played an essential role in HP tuning for RL algorithms to effectively solve different control tasks.

Detection of Auditory Brainstem Response Peaks Using Image Processing Techniques in Infants with Normal Hearing Sensitivity

Introduction: The auditory brainstem response (ABR) is measured to find the brainstem-level peripheral auditory nerve system integrity in children having normal hearing. The Auditory Evoked Potential (AEP) is generated using acoustic stimuli. Interpreting these waves requires competence to avoid misdiagnosing hearing problems. Automating ABR test labeling with computer vision may reduce human error. Method: The ABR test results of 26 children aged 1 to 20 months with normal hearing in both ears were used. A new approach is suggested for automatically calculating the peaks of waves of different intensities (in decibels). The procedure entails acquiring wave images from an Audera device using the Color Thresholder method, segmenting each wave as a single wave image using the Image Region Analyzer application, converting all wave images into waves using Image Processing (IP) techniques, and finally calculating the latency of the peaks for each wave to be used by an audiologist for diagnosing the disease. Findings: Image processing techniques were able to detect 1, 3, and 5 waves in the diagnosis field with accuracy (0.82), (0.98), and (0.98), respectively, and its precision for waves 1, 3, and 5, were respectively (0.32), (0.97) and (0.87). This evaluation also worked well in the thresholding part and 82.7 % correctly detected the ABR waves. Conclusion: Our findings indicate that the audiology test battery suite can be made more accurate, quick, and error-free by using technology to automatically detect and label ABR waves.