Large Language Models for Mental Health Diagnostic Assessments: Exploring The Potential of Large Language Models for Assisting with Mental Health Diagnostic Assessments -- The Depression and Anxiety Case

Large language models (LLMs) are increasingly attracting the attention of healthcare professionals for their potential to assist in diagnostic assessments, which could alleviate the strain on the healthcare system caused by a high patient load and a shortage of providers. For LLMs to be effective in supporting diagnostic assessments, it is essential that they closely replicate the standard diagnostic procedures used by clinicians. In this paper, we specifically examine the diagnostic assessment processes described in the Patient Health Questionnaire-9 (PHQ-9) for major depressive disorder (MDD) and the Generalized Anxiety Disorder-7 (GAD-7) questionnaire for generalized anxiety disorder (GAD). We investigate various prompting and fine-tuning techniques to guide both proprietary and open-source LLMs in adhering to these processes, and we evaluate the agreement between LLM-generated diagnostic outcomes and expert-validated ground truth. For fine-tuning, we utilize the Mentalllama and Llama models, while for prompting, we experiment with proprietary models like GPT-3.5 and GPT-4o, as well as open-source models such as llama-3.1-8b and mixtral-8x7b.

GEAR-Up: Generative AI and External Knowledge-based Retrieval Upgrading Scholarly Article Searches for Systematic Reviews

Systematic reviews (SRs) - the librarian-assisted literature survey of scholarly articles takes time and requires significant human resources. Given the ever-increasing volume of published studies, applying existing computing and informatics technology can decrease this time and resource burden. Due to the revolutionary advances in (1) Generative AI such as ChatGPT, and (2) External knowledge-augmented information extraction efforts such as Retrieval-Augmented Generation, In this work, we explore the use of techniques from (1) and (2) for SR. We demonstrate a system that takes user queries, performs query expansion to obtain enriched context (includes additional terms and definitions by querying language models and knowledge graphs), and uses this context to search for articles on scholarly databases to retrieve articles. We perform qualitative evaluations of our system through comparison against sentinel (ground truth) articles provided by an in-house librarian. The demo can be found at: https://youtu.be/zMdP56GJ9mU.