Source-Aware Spatial-Spectral-Integrated Double U-Net for Image Fusion

In image fusion tasks, pictures from different sources possess distinctive properties, therefore treating them equally will lead to inadequate feature extracting. Besides, multi-scaled networks capture information more sufficiently than single-scaled models in pixel-wised problems. In light of these factors, we propose a source-aware spatial-spectral-integrated double U-shaped network called $\rm{(SU)^2}$Net. The network is mainly composed of a spatial U-net and a spectral U-net, which learn spatial details and spectral characteristics discriminately and hierarchically. In contrast with most previous works that simply apply concatenation to integrate spatial and spectral information, a novel structure named the spatial-spectral block (called $\rm{S^2}$Block) is specially designed to merge feature maps from different sources effectively. Experiment results show that our method outperforms the representative state-of-the-art (SOTA) approaches in both quantitative and qualitative evaluations for a variety of image fusion missions, including remote sensing pansharpening and hyperspectral image super-resolution (HISR).

Wasserstein Adversarial Autoencoders for Knowledge Graph Embedding based Drug-Drug Interaction Prediction

Interaction between pharmacological agents can trigger unexpected adverse events. Capturing richer and more comprehensive information about drug-drug interactions (DDI) is one of the key tasks in public health and drug development. Recently, several knowledge graph embedding approaches have received increasing attention in the DDI domain due to their capability of projecting drugs and interactions into a low-dimensional feature space for predicting links and classifying triplets. However, existing methods only apply a uniformly random mode to construct negative samples. As a consequence, these samples are often too simplistic to train an effective model. In this paper, we propose a new knowledge graph embedding framework by introducing adversarial autoencoders (AAE) based on Wasserstein distances and Gumbel-Softmax relaxation for drug-drug interactions tasks. In our framework, the autoencoder is employed to generate high-quality negative samples and the hidden vector of the autoencoder is regarded as a plausible drug candidate. Afterwards, the discriminator learns the embeddings of drugs and interactions based on both positive and negative triplets. Meanwhile, in order to solve vanishing gradient problems on the discrete representation--an inherent flaw in traditional generative models--we utilize the Gumbel-Softmax relaxation and the Wasserstein distance to train the embedding model steadily. We empirically evaluate our method on two tasks, link prediction and DDI classification. The experimental results show that our framework can attain significant improvements and noticeably outperform competitive baselines.