Backdoor Attack with Mode Mixture Latent Modification

Backdoor attacks become a significant security concern for deep neural networks in recent years. An image classification model can be compromised if malicious backdoors are injected into it. This corruption will cause the model to function normally on clean images but predict a specific target label when triggers are present. Previous research can be categorized into two genres: poisoning a portion of the dataset with triggered images for users to train the model from scratch, or training a backdoored model alongside a triggered image generator. Both approaches require significant amount of attackable parameters for optimization to establish a connection between the trigger and the target label, which may raise suspicions as more people become aware of the existence of backdoor attacks. In this paper, we propose a backdoor attack paradigm that only requires minimal alterations (specifically, the output layer) to a clean model in order to inject the backdoor under the guise of fine-tuning. To achieve this, we leverage mode mixture samples, which are located between different modes in latent space, and introduce a novel method for conducting backdoor attacks. We evaluate the effectiveness of our method on four popular benchmark datasets: MNIST, CIFAR-10, GTSRB, and TinyImageNet.

Large language models improve Alzheimer's disease diagnosis using multi-modality data

In diagnosing challenging conditions such as Alzheimer's disease (AD), imaging is an important reference. Non-imaging patient data such as patient information, genetic data, medication information, cognitive and memory tests also play a very important role in diagnosis. Effect. However, limited by the ability of artificial intelligence models to mine such information, most of the existing models only use multi-modal image data, and cannot make full use of non-image data. We use a currently very popular pre-trained large language model (LLM) to enhance the model's ability to utilize non-image data, and achieved SOTA results on the ADNI dataset.

Classification of lung nodules in CT images based on Wasserstein distance in differential geometry

Lung nodules are commonly detected in screening for patients with a risk for lung cancer. Though the status of large nodules can be easily diagnosed by fine needle biopsy or bronchoscopy, small nodules are often difficult to classify on computed tomography (CT). Recent works have shown that shape analysis of lung nodules can be used to differentiate benign lesions from malignant ones, though existing methods are limited in their sensitivity and specificity. In this work we introduced a new 3D shape analysis within the framework of differential geometry to calculate the Wasserstein distance between benign and malignant lung nodules to derive an accurate classification scheme. The Wasserstein distance between the nodules is calculated based on our new spherical optimal mass transport, this new algorithm works directly on sphere by using spherical metric, which is much more accurate and efficient than previous methods. In the process of deformation, the area-distortion factor gives a probability measure on the unit sphere, which forms the Wasserstein space. From known cases of benign and malignant lung nodules, we can calculate a unique optimal mass transport map between their correspondingly deformed Wasserstein spaces. This transportation cost defines the Wasserstein distance between them and can be used to classify new lung nodules into either the benign or malignant class. To the best of our knowledge, this is the first work that utilizes Wasserstein distance for lung nodule classification. The advantages of Wasserstein distance are it is invariant under rigid motions and scalings, thus it intrinsically measures shape distance even when the underlying shapes are of high complexity, making it well suited to classify lung nodules as they have different sizes, orientations, and appearances.