GLFC: Unified Global-Local Feature and Contrast Learning with Mamba-Enhanced UNet for Synthetic CT Generation from CBCT

Generating synthetic Computed Tomography (CT) images from Cone Beam Computed Tomography (CBCT) is desirable for improving the image quality of CBCT. Existing synthetic CT (sCT) generation methods using Convolutional Neural Networks (CNN) and Transformers often face difficulties in effectively capturing both global and local features and contrasts for high-quality sCT generation. In this work, we propose a Global-Local Feature and Contrast learning (GLFC) framework for sCT generation. First, a Mamba-Enhanced UNet (MEUNet) is introduced by integrating Mamba blocks into the skip connections of a high-resolution UNet for effective global and local feature learning. Second, we propose a Multiple Contrast Loss (MCL) that calculates synthetic loss at different intensity windows to improve quality for both soft tissues and bone regions. Experiments on the SynthRAD2023 dataset demonstrate that GLFC improved the SSIM of sCT from 77.91% to 91.50% compared with the original CBCT, and significantly outperformed several existing methods for sCT generation. The code is available at https://github.com/intelland/GLFC

Towards Scalable Distributed Training of Deep Learning on Public Cloud Clusters

Distributed training techniques have been widely deployed in large-scale deep neural networks (DNNs) training on dense-GPU clusters. However, on public cloud clusters, due to the moderate inter-connection bandwidth between instances, traditional state-of-the-art distributed training systems cannot scale well in training large-scale models. In this paper, we propose a new computing and communication efficient top-k sparsification communication library for distributed training. To further improve the system scalability, we optimize I/O by proposing a simple yet efficient multi-level data caching mechanism and optimize the update operation by introducing a novel parallel tensor operator. Experimental results on a 16-node Tencent Cloud cluster (each node with 8 Nvidia Tesla V100 GPUs) show that our system achieves 25%-40% faster than existing state-of-the-art systems on CNNs and Transformer. We finally break the record on DAWNBench on training ResNet-50 to 93% top-5 accuracy on ImageNet.