Infrastructure for AI Agents

Increasingly many AI systems can plan and execute interactions in open-ended environments, such as making phone calls or buying online goods. As developers grow the space of tasks that such AI agents can accomplish, we will need tools both to unlock their benefits and manage their risks. Current tools are largely insufficient because they are not designed to shape how agents interact with existing institutions (e.g., legal and economic systems) or actors (e.g., digital service providers, humans, other AI agents). For example, alignment techniques by nature do not assure counterparties that some human will be held accountable when a user instructs an agent to perform an illegal action. To fill this gap, we propose the concept of agent infrastructure: technical systems and shared protocols external to agents that are designed to mediate and influence their interactions with and impacts on their environments. Agent infrastructure comprises both new tools and reconfigurations or extensions of existing tools. For example, to facilitate accountability, protocols that tie users to agents could build upon existing systems for user authentication, such as OpenID. Just as the Internet relies on infrastructure like HTTPS, we argue that agent infrastructure will be similarly indispensable to ecosystems of agents. We identify three functions for agent infrastructure: 1) attributing actions, properties, and other information to specific agents, their users, or other actors; 2) shaping agents' interactions; and 3) detecting and remedying harmful actions from agents. We propose infrastructure that could help achieve each function, explaining use cases, adoption, limitations, and open questions. Making progress on agent infrastructure can prepare society for the adoption of more advanced agents.

AI-Assisted Discovery of Quantitative and Formal Models in Social Science

In social science, formal and quantitative models, such as ones describing economic growth and collective action, are used to formulate mechanistic explanations, provide predictions, and uncover questions about observed phenomena. Here, we demonstrate the use of a machine learning system to aid the discovery of symbolic models that capture nonlinear and dynamical relationships in social science datasets. By extending neuro-symbolic methods to find compact functions and differential equations in noisy and longitudinal data, we show that our system can be used to discover interpretable models from real-world data in economics and sociology. Augmenting existing workflows with symbolic regression can help uncover novel relationships and explore counterfactual models during the scientific process. We propose that this AI-assisted framework can bridge parametric and non-parametric models commonly employed in social science research by systematically exploring the space of nonlinear models and enabling fine-grained control over expressivity and interpretability.

Towards Multicellular Biological Deep Neural Nets Based on Transcriptional Regulation

Artificial neurons built on synthetic gene networks have potential applications ranging from complex cellular decision-making to bioreactor regulation. Furthermore, due to the high information throughput of natural systems, it provides an interesting candidate for biologically-based supercomputing and analog simulations of traditionally intractable problems. In this paper, we propose an architecture for constructing multicellular neural networks and programmable nonlinear systems. We design an artificial neuron based on gene regulatory networks and optimize its dynamics for modularity. Using gene expression models, we simulate its ability to perform arbitrary linear classifications from multiple inputs. Finally, we construct a two-layer neural network to demonstrate scalability and nonlinear decision boundaries and discuss future directions for utilizing uncontrolled neurons in computational tasks.