AdaMHF: Adaptive Multimodal Hierarchical Fusion for Survival Prediction

The integration of pathologic images and genomic data for survival analysis has gained increasing attention with advances in multimodal learning. However, current methods often ignore biological characteristics, such as heterogeneity and sparsity, both within and across modalities, ultimately limiting their adaptability to clinical practice. To address these challenges, we propose AdaMHF: Adaptive Multimodal Hierarchical Fusion, a framework designed for efficient, comprehensive, and tailored feature extraction and fusion. AdaMHF is specifically adapted to the uniqueness of medical data, enabling accurate predictions with minimal resource consumption, even under challenging scenarios with missing modalities. Initially, AdaMHF employs an experts expansion and residual structure to activate specialized experts for extracting heterogeneous and sparse features. Extracted tokens undergo refinement via selection and aggregation, reducing the weight of non-dominant features while preserving comprehensive information. Subsequently, the encoded features are hierarchically fused, allowing multi-grained interactions across modalities to be captured. Furthermore, we introduce a survival prediction benchmark designed to resolve scenarios with missing modalities, mirroring real-world clinical conditions. Extensive experiments on TCGA datasets demonstrate that AdaMHF surpasses current state-of-the-art (SOTA) methods, showcasing exceptional performance in both complete and incomplete modality settings.

PatchScaler: An Efficient Patch-independent Diffusion Model for Super-Resolution

Diffusion models significantly improve the quality of super-resolved images with their impressive content generation capabilities. However, the huge computational costs limit the applications of these methods.Recent efforts have explored reasonable inference acceleration to reduce the number of sampling steps, but the computational cost remains high as each step is performed on the entire image.This paper introduces PatchScaler, a patch-independent diffusion-based single image super-resolution (SR) method, designed to enhance the efficiency of the inference process.The proposed method is motivated by the observation that not all the image patches within an image need the same sampling steps for reconstructing high-resolution images.Based on this observation, we thus develop a Patch-adaptive Group Sampling (PGS) to divide feature patches into different groups according to the patch-level reconstruction difficulty and dynamically assign an appropriate sampling configuration for each group so that the inference speed can be better accelerated.In addition, to improve the denoising ability at each step of the sampling, we develop a texture prompt to guide the estimations of the diffusion model by retrieving high-quality texture priors from a patch-independent reference texture memory.Experiments show that our PatchScaler achieves favorable performance in both quantitative and qualitative evaluations with fast inference speed.Our code and model are available at \url{https://github.com/yongliuy/PatchScaler}.