Feature transforms for image data augmentation

A problem with Convolutional Neural Networks (CNNs) is that they require large datasets to obtain adequate robustness; on small datasets, they are prone to overfitting. Many methods have been proposed to overcome this shortcoming with CNNs. In cases where additional samples cannot easily be collected, a common approach is to generate more data points from existing data using an augmentation technique. In image classification, many augmentation approaches utilize simple image manipulation algorithms. In this work, we build ensembles on the data level by adding images generated by combining fourteen augmentation approaches, three of which are proposed here for the first time. These novel methods are based on the Fourier Transform (FT), the Radon Transform (RT) and the Discrete Cosine Transform (DCT). Pretrained ResNet50 networks are finetuned on training sets that include images derived from each augmentation method. These networks and several fusions are evaluated and compared across eleven benchmarks. Results show that building ensembles on the data level by combining different data augmentation methods produce classifiers that not only compete competitively against the state-of-the-art but often surpass the best approaches reported in the literature.

Deep ensembles in bioimage segmentation

Semantic segmentation consists in classifying each pixel of an image by assigning it to a specific label chosen from a set of all the available ones. During the last few years, a lot of attention shifted to this kind of task. Many computer vision researchers tried to apply autoencoder structures to develop models that can learn the semantics of the image as well as a low-level representation of it. In an autoencoder architecture, given an input, an encoder computes a low dimensional representation of the input that is then used by a decoder to reconstruct the original data. In this work, we propose an ensemble of convolutional neural networks (CNNs). In ensemble methods, many different models are trained and then used for classification, the ensemble aggregates the outputs of the single classifiers. The approach leverages on differences of various classifiers to improve the performance of the whole system. Diversity among the single classifiers is enforced by using different loss functions. In particular, we present a new loss function that results from the combination of Dice and Structural Similarity Index. The proposed ensemble is implemented by combining different backbone networks using the DeepLabV3+ and HarDNet environment. The proposal is evaluated through an extensive empirical evaluation on two real-world scenarios: polyp and skin segmentation. All the code is available online at https://github.com/LorisNanni.

Gated recurrent units and temporal convolutional network for multilabel classification

Multilabel learning tackles the problem of associating a sample with multiple class labels. This work proposes a new ensemble method for managing multilabel classification: the core of the proposed approach combines a set of gated recurrent units and temporal convolutional neural networks trained with variants of the Adam optimization approach. Multiple Adam variants, including novel one proposed here, are compared and tested; these variants are based on the difference between present and past gradients, with step size adjusted for each parameter. The proposed neural network approach is also combined with Incorporating Multiple Clustering Centers (IMCC), which further boosts classification performance. Multiple experiments on nine data sets representing a wide variety of multilabel tasks demonstrate the robustness of our best ensemble, which is shown to outperform the state-of-the-art. The MATLAB code for generating the best ensembles in the experimental section will be available at https://github.com/LorisNanni.

High performing ensemble of convolutional neural networks for insect pest image detection

Pest infestation is a major cause of crop damage and lost revenues worldwide. Automatic identification of invasive insects would greatly speedup the identification of pests and expedite their removal. In this paper, we generate ensembles of CNNs based on different topologies (ResNet50, GoogleNet, ShuffleNet, MobileNetv2, and DenseNet201) altered by random selection from a simple set of data augmentation methods or optimized with different Adam variants for pest identification. Two new Adam algorithms for deep network optimization based on DGrad are proposed that introduce a scaling factor in the learning rate. Sets of the five CNNs that vary in either data augmentation or the type of Adam optimization were trained on both the Deng (SMALL) and the large IP102 pest data sets. Ensembles were compared and evaluated using three performance indicators. The best performing ensemble, which combined the CNNs using the different augmentation methods and the two new Adam variants proposed here, achieved state of the art on both insect data sets: 95.52% on Deng and 73.46% on IP102, a score on Deng that competed with human expert classifications. Additional tests were performed on data sets for medical imagery classification that further validated the robustness and power of the proposed Adam optimization variants. All MATLAB source code is available at https://github.com/LorisNanni/.

Deep Features for training Support Vector Machine

Features play a crucial role in computer vision. Initially designed to detect salient elements by means of handcrafted algorithms, features are now often learned by different layers in Convolutional Neural Networks (CNNs). This paper develops a generic computer vision system based on features extracted from trained CNNs. Multiple learned features are combined into a single structure to work on different image classification tasks. The proposed system was experimentally derived by testing several approaches for extracting features from the inner layers of CNNs and using them as inputs to SVMs that are then combined by sum rule. Dimensionality reduction techniques are used to reduce the high dimensionality of inner layers. The resulting vision system is shown to significantly boost the performance of standard CNNs across a large and diverse collection of image data sets. An ensemble of different topologies using the same approach obtains state-of-the-art results on a virus data set.

Deep ensembles based on Stochastic Activation Selection for Polyp Segmentation

Semantic segmentation has a wide array of applications ranging from medical-image analysis, scene understanding, autonomous driving and robotic navigation. This work deals with medical image segmentation and in particular with accurate polyp detection and segmentation during colonoscopy examinations. Several convolutional neural network architectures have been proposed to effectively deal with this task and with the problem of segmenting objects at different scale input. The basic architecture in image segmentation consists of an encoder and a decoder: the first uses convolutional filters to extract features from the image, the second is responsible for generating the final output. In this work, we compare some variant of the DeepLab architecture obtained by varying the decoder backbone. We compare several decoder architectures, including ResNet, Xception, EfficentNet, MobileNet and we perturb their layers by substituting ReLU activation layers with other functions. The resulting methods are used to create deep ensembles which are shown to be very effective. Our experimental evaluations show that our best ensemble produces good segmentation results by achieving high evaluation scores with a dice coefficient of 0.884, and a mean Intersection over Union (mIoU) of 0.818 for the Kvasir-SEG dataset. To improve reproducibility and research efficiency the MATLAB source code used for this research is available at GitHub: https://github.com/LorisNanni.

Comparison of different convolutional neural network activation functions and methods for building ensembles

Recently, much attention has been devoted to finding highly efficient and powerful activation functions for CNN layers. Because activation functions inject different nonlinearities between layers that affect performance, varying them is one method for building robust ensembles of CNNs. The objective of this study is to examine the performance of CNN ensembles made with different activation functions, including six new ones presented here: 2D Mexican ReLU, TanELU, MeLU+GaLU, Symmetric MeLU, Symmetric GaLU, and Flexible MeLU. The highest performing ensemble was built with CNNs having different activation layers that randomly replaced the standard ReLU. A comprehensive evaluation of the proposed approach was conducted across fifteen biomedical data sets representing various classification tasks. The proposed method was tested on two basic CNN architectures: Vgg16 and ResNet50. Results demonstrate the superiority in performance of this approach. The MATLAB source code for this study will be available at https://github.com/LorisNanni.

Exploiting Adam-like Optimization Algorithms to Improve the Performance of Convolutional Neural Networks

Stochastic gradient descent (SGD) is the main approach for training deep networks: it moves towards the optimum of the cost function by iteratively updating the parameters of a model in the direction of the gradient of the loss evaluated on a minibatch. Several variants of SGD have been proposed to make adaptive step sizes for each parameter (adaptive gradient) and take into account the previous updates (momentum). Among several alternative of SGD the most popular are AdaGrad, AdaDelta, RMSProp and Adam which scale coordinates of the gradient by square roots of some form of averaging of the squared coordinates in the past gradients and automatically adjust the learning rate on a parameter basis. In this work, we compare Adam based variants based on the difference between the present and the past gradients, the step size is adjusted for each parameter. We run several tests benchmarking proposed methods using medical image data. The experiments are performed using ResNet50 architecture neural network. Moreover, we have tested ensemble of networks and the fusion with ResNet50 trained with stochastic gradient descent. To combine the set of ResNet50 the simple sum rule has been applied. Proposed ensemble obtains very high performance, it obtains accuracy comparable or better than actual state of the art. To improve reproducibility and research efficiency the MATLAB source code used for this research is available at GitHub: https://github.com/LorisNanni.

Neural networks for Anatomical Therapeutic Chemical (ATC)

Motivation: Automatic Anatomical Therapeutic Chemical (ATC) classification is a critical and highly competitive area of research in bioinformatics because of its potential for expediting drug develop-ment and research. Predicting an unknown compound's therapeutic and chemical characteristics ac-cording to how these characteristics affect multiple organs/systems makes automatic ATC classifica-tion a challenging multi-label problem. Results: In this work, we propose combining multiple multi-label classifiers trained on distinct sets of features, including sets extracted from a Bidirectional Long Short-Term Memory Network (BiLSTM). Experiments demonstrate the power of this approach, which is shown to outperform the best methods reported in the literature, including the state-of-the-art developed by the fast.ai research group. Availability: All source code developed for this study is available at https://github.com/LorisNanni. Contact: loris.nanni@unipd.it

Deep learning and hand-crafted features for virus image classification

In this work, we present an ensemble of descriptors for the classification of transmission electron microscopy images of viruses. We propose to combine handcrafted and deep learning approaches for virus image classification. The set of handcrafted is mainly based on Local Binary Pattern variants, for each descriptor a different Support Vector Machine is trained, then the set of classifiers is combined by sum rule. The deep learning approach is a densenet201 pretrained on ImageNet and then tuned in the virus dataset, the net is used as features extractor for feeding another Support Vector Machine, in particular the last average pooling layer is used as feature extractor. Finally, classifiers trained on handcrafted features and classifier trained on deep learning features are combined by sum rule. The proposed fusion strongly boosts the performance obtained by each stand-alone approach, obtaining state of the art performance.