Boosting Sclera Segmentation through Semi-supervised Learning with Fewer Labels

Sclera segmentation is crucial for developing automatic eye-related medical computer-aided diagnostic systems, as well as for personal identification and verification, because the sclera contains distinct personal features. Deep learning-based sclera segmentation has achieved significant success compared to traditional methods that rely on hand-crafted features, primarily because it can autonomously extract critical output-related features without the need to consider potential physical constraints. However, achieving accurate sclera segmentation using these methods is challenging due to the scarcity of high-quality, fully labeled datasets, which depend on costly, labor-intensive medical acquisition and expertise. To address this challenge, this paper introduces a novel sclera segmentation framework that excels with limited labeled samples. Specifically, we employ a semi-supervised learning method that integrates domain-specific improvements and image-based spatial transformations to enhance segmentation performance. Additionally, we have developed a real-world eye diagnosis dataset to enrich the evaluation process. Extensive experiments on our dataset and two additional public datasets demonstrate the effectiveness and superiority of our proposed method, especially with significantly fewer labeled samples.

Federated Distillation for Medical Image Classification: Towards Trustworthy Computer-Aided Diagnosis

Medical image classification plays a crucial role in computer-aided clinical diagnosis. While deep learning techniques have significantly enhanced efficiency and reduced costs, the privacy-sensitive nature of medical imaging data complicates centralized storage and model training. Furthermore, low-resource healthcare organizations face challenges related to communication overhead and efficiency due to increasing data and model scales. This paper proposes a novel privacy-preserving medical image classification framework based on federated learning to address these issues, named FedMIC. The framework enables healthcare organizations to learn from both global and local knowledge, enhancing local representation of private data despite statistical heterogeneity. It provides customized models for organizations with diverse data distributions while minimizing communication overhead and improving efficiency without compromising performance. Our FedMIC enhances robustness and practical applicability under resource-constrained conditions. We demonstrate FedMIC's effectiveness using four public medical image datasets for classical medical image classification tasks.

CMT: Interpretable Model for Rapid Recognition Pneumonia from Chest X-Ray Images by Fusing Low Complexity Multilevel Attention Mechanism

Chest imaging plays an essential role in diagnosing and predicting patients with COVID-19 with evidence of worsening respiratory status. Many deep learning-based diagnostic models for pneumonia have been developed to enable computer-aided diagnosis. However, the long training and inference time make them inflexible. In addition, the lack of interpretability reduces their credibility in clinical medical practice. This paper presents CMT, a model with interpretability and rapid recognition of pneumonia, especially COVID-19 positive. Multiple convolutional layers in CMT are first used to extract features in CXR images, and then Transformer is applied to calculate the possibility of each symptom. To improve the model's generalization performance and to address the problem of sparse medical image data, we propose Feature Fusion Augmentation (FFA), a plug-and-play method for image augmentation. It fuses the features of the two images to varying degrees to produce a new image that does not deviate from the original distribution. Furthermore, to reduce the computational complexity and accelerate the convergence, we propose Multilevel Multi-Head Self-Attention (MMSA), which computes attention on different levels to establish the relationship between global and local features. It significantly improves the model performance while substantially reducing its training and inference time. Experimental results on the largest COVID-19 dataset show the proposed CMT has state-of-the-art performance. The effectiveness of FFA and MMSA is demonstrated in the ablation experiments. In addition, the weights and feature activation maps of the model inference process are visualized to show the CMT's interpretability.