Stable Diffusion Segmentation for Biomedical Images with Single-step Reverse Process

Diffusion models have demonstrated their effectiveness across various generative tasks. However, when applied to medical image segmentation, these models encounter several challenges, including significant resource and time requirements. They also necessitate a multi-step reverse process and multiple samples to produce reliable predictions. To address these challenges, we introduce the first latent diffusion segmentation model, named SDSeg, built upon stable diffusion (SD). SDSeg incorporates a straightforward latent estimation strategy to facilitate a single-step reverse process and utilizes latent fusion concatenation to remove the necessity for multiple samples. Extensive experiments indicate that SDSeg surpasses existing state-of-the-art methods on five benchmark datasets featuring diverse imaging modalities. Remarkably, SDSeg is capable of generating stable predictions with a solitary reverse step and sample, epitomizing the model's stability as implied by its name. The code is available at https://github.com/lin-tianyu/Stable-Diffusion-Seg

Exploring Low-Resource Medical Image Classification with Weakly Supervised Prompt Learning

Most advances in medical image recognition supporting clinical auxiliary diagnosis meet challenges due to the low-resource situation in the medical field, where annotations are highly expensive and professional. This low-resource problem can be alleviated by leveraging the transferable representations of large-scale pre-trained vision-language models via relevant medical text prompts. However, existing pre-trained vision-language models require domain experts to carefully design the medical prompts, which greatly increases the burden on clinicians. To address this problem, we propose a weakly supervised prompt learning method MedPrompt to automatically generate medical prompts, which includes an unsupervised pre-trained vision-language model and a weakly supervised prompt learning model. The unsupervised pre-trained vision-language model utilizes the natural correlation between medical images and corresponding medical texts for pre-training, without any manual annotations. The weakly supervised prompt learning model only utilizes the classes of images in the dataset to guide the learning of the specific class vector in the prompt, while the learning of other context vectors in the prompt requires no manual annotations for guidance. To the best of our knowledge, this is the first model to automatically generate medical prompts. With these prompts, the pre-trained vision-language model can be freed from the strong expert dependency of manual annotation and manual prompt design. Experimental results show that the model using our automatically generated prompts outperforms its full-shot learning hand-crafted prompts counterparts with only a minimal number of labeled samples for few-shot learning, and reaches superior or comparable accuracy on zero-shot image classification. The proposed prompt generator is lightweight and therefore can be embedded into any network architecture.

Intensive Vision-guided Network for Radiology Report Generation

Automatic radiology report generation is booming due to its huge application potential for the healthcare industry. However, existing computer vision and natural language processing approaches to tackle this problem are limited in two aspects. First, when extracting image features, most of them neglect multi-view reasoning in vision and model single-view structure of medical images, such as space-view or channel-view. However, clinicians rely on multi-view imaging information for comprehensive judgment in daily clinical diagnosis. Second, when generating reports, they overlook context reasoning with multi-modal information and focus on pure textual optimization utilizing retrieval-based methods. We aim to address these two issues by proposing a model that better simulates clinicians' perspectives and generates more accurate reports. Given the above limitation in feature extraction, we propose a Globally-intensive Attention (GIA) module in the medical image encoder to simulate and integrate multi-view vision perception. GIA aims to learn three types of vision perception: depth view, space view, and pixel view. On the other hand, to address the above problem in report generation, we explore how to involve multi-modal signals to generate precisely matched reports, i.e., how to integrate previously predicted words with region-aware visual content in next word prediction. Specifically, we design a Visual Knowledge-guided Decoder (VKGD), which can adaptively consider how much the model needs to rely on visual information and previously predicted text to assist next word prediction. Hence, our final Intensive Vision-guided Network (IVGN) framework includes a GIA-guided Visual Encoder and the VKGD. Experiments on two commonly-used datasets IU X-Ray and MIMIC-CXR demonstrate the superior ability of our method compared with other state-of-the-art approaches.

AdaNAS: Adaptively Post-processing with Self-supervised Neural Architecture Search for Ensemble Rainfall Forecasts

Previous post-processing studies on rainfall forecasts using numerical weather prediction (NWP) mainly focus on statistics-based aspects, while learning-based aspects are rarely investigated. Although some manually-designed models are proposed to raise accuracy, they are customized networks, which need to be repeatedly tried and verified, at a huge cost in time and labor. Therefore, a self-supervised neural architecture search (NAS) method without significant manual efforts called AdaNAS is proposed in this study to perform rainfall forecast post-processing and predict rainfall with high accuracy. In addition, we design a rainfall-aware search space to significantly improve forecasts for high-rainfall areas. Furthermore, we propose a rainfall-level regularization function to eliminate the effect of noise data during the training. Validation experiments have been performed under the cases of \emph{None}, \emph{Light}, \emph{Moderate}, \emph{Heavy} and \emph{Violent} on a large-scale precipitation benchmark named TIGGE. Finally, the average mean-absolute error (MAE) and average root-mean-square error (RMSE) of the proposed AdaNAS model are 0.98 and 2.04 mm/day, respectively. Additionally, the proposed AdaNAS model is compared with other neural architecture search methods and previous studies. Compared results reveal the satisfactory performance and superiority of the proposed AdaNAS model in terms of precipitation amount prediction and intensity classification. Concretely, the proposed AdaNAS model outperformed previous best-performing manual methods with MAE and RMSE improving by 80.5\% and 80.3\%, respectively.