Tolerance-Aware Deep Optics

Deep optics has emerged as a promising approach by co-designing optical elements with deep learning algorithms. However, current research typically overlooks the analysis and optimization of manufacturing and assembly tolerances. This oversight creates a significant performance gap between designed and fabricated optical systems. To address this challenge, we present the first end-to-end tolerance-aware optimization framework that incorporates multiple tolerance types into the deep optics design pipeline. Our method combines physics-informed modelling with data-driven training to enhance optical design by accounting for and compensating for structural deviations in manufacturing and assembly. We validate our approach through computational imaging applications, demonstrating results in both simulations and real-world experiments. We further examine how our proposed solution improves the robustness of optical systems and vision algorithms against tolerances through qualitative and quantitative analyses. Code and additional visual results are available at openimaginglab.github.io/LensTolerance.

Single-shot wide-field optical section imaging

Optical sectioning technology has been widely used in various fluorescence microscopes owing to its background removing capability. Here, a virtual HiLo based on edge detection (V-HiLo-ED) is proposed to achieve wide-field optical sectioning, which requires only single wide-field image. Compared with conventional optical sectioning technologies, its imaging speed can be increased by at least twice, meanwhile maintaining nice optical sectioning performance, low cost, and excellent artifact suppression capabilities. Furthermore, the new V-HiLo-ED can also be extended to other non-fluorescence imaging fields. This simple, cost-effective and easy-to-extend method will benefit many research and application fields that needs to remove out-of-focus blurred images.