A Look into Causal Effects under Entangled Treatment in Graphs: Investigating the Impact of Contact on MRSA Infection

Methicillin-resistant Staphylococcus aureus (MRSA) is a type of bacteria resistant to certain antibiotics, making it difficult to prevent MRSA infections. Among decades of efforts to conquer infectious diseases caused by MRSA, many studies have been proposed to estimate the causal effects of close contact (treatment) on MRSA infection (outcome) from observational data. In this problem, the treatment assignment mechanism plays a key role as it determines the patterns of missing counterfactuals -- the fundamental challenge of causal effect estimation. Most existing observational studies for causal effect learning assume that the treatment is assigned individually for each unit. However, on many occasions, the treatments are pairwisely assigned for units that are connected in graphs, i.e., the treatments of different units are entangled. Neglecting the entangled treatments can impede the causal effect estimation. In this paper, we study the problem of causal effect estimation with treatment entangled in a graph. Despite a few explorations for entangled treatments, this problem still remains challenging due to the following challenges: (1) the entanglement brings difficulties in modeling and leveraging the unknown treatment assignment mechanism; (2) there may exist hidden confounders which lead to confounding biases in causal effect estimation; (3) the observational data is often time-varying. To tackle these challenges, we propose a novel method NEAT, which explicitly leverages the graph structure to model the treatment assignment mechanism, and mitigates confounding biases based on the treatment assignment modeling. We also extend our method into a dynamic setting to handle time-varying observational data. Experiments on both synthetic datasets and a real-world MRSA dataset validate the effectiveness of the proposed method, and provide insights for future applications.

Data Selection for Fine-tuning Large Language Models Using Transferred Shapley Values

Although Shapley values have been shown to be highly effective for identifying harmful training instances, dataset size and model complexity constraints limit the ability to apply Shapley-based data valuation to fine-tuning large pre-trained language models. To address this, we propose TS-DShapley, an algorithm that reduces computational cost of Shapley-based data valuation through: 1) an efficient sampling-based method that aggregates Shapley values computed from subsets for valuation of the entire training set, and 2) a value transfer method that leverages value information extracted from a simple classifier trained using representations from the target language model. Our experiments applying TS-DShapley to select data for fine-tuning BERT-based language models on benchmark natural language understanding (NLU) datasets show that TS-DShapley outperforms existing data selection methods. Further, TS-DShapley can filter fine-tuning data to increase language model performance compared to training with the full fine-tuning dataset.