Tri-VQA: Triangular Reasoning Medical Visual Question Answering for Multi-Attribute Analysis

The intersection of medical Visual Question Answering (Med-VQA) is a challenging research topic with advantages including patient engagement and clinical expert involvement for second opinions. However, existing Med-VQA methods based on joint embedding fail to explain whether their provided results are based on correct reasoning or coincidental answers, which undermines the credibility of VQA answers. In this paper, we investigate the construction of a more cohesive and stable Med-VQA structure. Motivated by causal effect, we propose a novel Triangular Reasoning VQA (Tri-VQA) framework, which constructs reverse causal questions from the perspective of "Why this answer?" to elucidate the source of the answer and stimulate more reasonable forward reasoning processes. We evaluate our method on the Endoscopic Ultrasound (EUS) multi-attribute annotated dataset from five centers, and test it on medical VQA datasets. Experimental results demonstrate the superiority of our approach over existing methods. Our codes and pre-trained models are available at https://anonymous.4open.science/r/Tri_VQA.

MDA: An Interpretable Multi-Modal Fusion with Missing Modalities and Intrinsic Noise

Multi-modal fusion is crucial in medical data research, enabling a comprehensive understanding of diseases and improving diagnostic performance by combining diverse modalities. However, multi-modal fusion faces challenges, including capturing interactions between modalities, addressing missing modalities, handling erroneous modal information, and ensuring interpretability. Many existing researchers tend to design different solutions for these problems, often overlooking the commonalities among them. This paper proposes a novel multi-modal fusion framework that achieves adaptive adjustment over the weights of each modality by introducing the Modal-Domain Attention (MDA). It aims to facilitate the fusion of multi-modal information while allowing for the inclusion of missing modalities or intrinsic noise, thereby enhancing the representation of multi-modal data. We provide visualizations of accuracy changes and MDA weights by observing the process of modal fusion, offering a comprehensive analysis of its interpretability. Extensive experiments on various gastrointestinal disease benchmarks, the proposed MDA maintains high accuracy even in the presence of missing modalities and intrinsic noise. One thing worth mentioning is that the visualization of MDA is highly consistent with the conclusions of existing clinical studies on the dependence of different diseases on various modalities. Code and dataset will be made available.

The Typical Behavior of Bandit Algorithms

We establish strong laws of large numbers and central limit theorems for the regret of two of the most popular bandit algorithms: Thompson sampling and UCB. Here, our characterizations of the regret distribution complement the characterizations of the tail of the regret distribution recently developed by Fan and Glynn (2021) (arXiv:2109.13595). The tail characterizations there are associated with atypical bandit behavior on trajectories where the optimal arm mean is under-estimated, leading to mis-identification of the optimal arm and large regret. In contrast, our SLLN's and CLT's here describe the typical behavior and fluctuation of regret on trajectories where the optimal arm mean is properly estimated. We find that Thompson sampling and UCB satisfy the same SLLN and CLT, with the asymptotics of both the SLLN and the (mean) centering sequence in the CLT matching the asymptotics of expected regret. Both the mean and variance in the CLT grow at $\log(T)$ rates with the time horizon $T$. Asymptotically as $T \to \infty$, the variability in the number of plays of each sub-optimal arm depends only on the rewards received for that arm, which indicates that each sub-optimal arm contributes independently to the overall CLT variance.

The Fragility of Optimized Bandit Algorithms

Much of the literature on optimal design of bandit algorithms is based on minimization of expected regret. It is well known that designs that are optimal over certain exponential families can achieve expected regret that grows logarithmically in the number of arm plays, at a rate governed by the Lai-Robbins lower bound. In this paper, we show that when one uses such optimized designs, the associated algorithms necessarily have the undesirable feature that the tail of the regret distribution behaves like that of a truncated Cauchy distribution. Furthermore, for $p>1$, the $p$'th moment of the regret distribution grows much faster than poly-logarithmically, in particular as a power of the number of sub-optimal arm plays. We show that optimized Thompson sampling and UCB bandit designs are also fragile, in the sense that when the problem is even slightly mis-specified, the regret can grow much faster than the conventional theory suggests. Our arguments are based on standard change-of-measure ideas, and indicate that the most likely way that regret becomes larger than expected is when the optimal arm returns below-average rewards in the first few arm plays that make that arm appear to be sub-optimal, thereby causing the algorithm to sample a truly sub-optimal arm much more than would be optimal.

Diffusion Approximations for Thompson Sampling

We study the behavior of Thompson sampling from the perspective of weak convergence. In the regime where the gaps between arm means scale as $1/\sqrt{n}$ with the time horizon $n$, we show that the dynamics of Thompson sampling evolve according to discrete versions of SDEs and random ODEs. As $n \to \infty$, we show that the dynamics converge weakly to solutions of the corresponding SDEs and random ODEs. (Recently, Wager and Xu (arXiv:2101.09855) independently proposed this regime and developed similar SDE and random ODE approximations.) Our weak convergence theory covers both the classical multi-armed and linear bandit settings, and can be used, for instance, to obtain insight about the characteristics of the regret distribution when there is information sharing among arms, as well as the effects of variance estimation, model mis-specification and batched updates in bandit learning. Our theory is developed from first-principles and can also be adapted to analyze other sampling-based bandit algorithms.