Limited-View Photoacoustic Imaging Reconstruction Via High-quality Self-supervised Neural Representation

In practical applications within the human body, it is often challenging to fully encompass the target tissue or organ, necessitating the use of limited-view arrays, which can lead to the loss of crucial information. Addressing the reconstruction of photoacoustic sensor signals in limited-view detection spaces has become a focal point of current research. In this study, we introduce a self-supervised network termed HIgh-quality Self-supervised neural representation (HIS), which tackles the inverse problem of photoacoustic imaging to reconstruct high-quality photoacoustic images from sensor data acquired under limited viewpoints. We regard the desired reconstructed photoacoustic image as an implicit continuous function in 2D image space, viewing the pixels of the image as sparse discrete samples. The HIS's objective is to learn the continuous function from limited observations by utilizing a fully connected neural network combined with Fourier feature position encoding. By simply minimizing the error between the network's predicted sensor data and the actual sensor data, HIS is trained to represent the observed continuous model. The results indicate that the proposed HIS model offers superior image reconstruction quality compared to three commonly used methods for photoacoustic image reconstruction.

Sparse-view Signal-domain Photoacoustic Tomography Reconstruction Method Based on Neural Representation

Photoacoustic tomography is a hybrid biomedical technology, which combines the advantages of acoustic and optical imaging. However, for the conventional image reconstruction method, the image quality is affected obviously by artifacts under the condition of sparse sampling. in this paper, a novel model-based sparse reconstruction method via implicit neural representation was proposed for improving the image quality reconstructed from sparse data. Specially, the initial acoustic pressure distribution was modeled as a continuous function of spatial coordinates, and parameterized by a multi-layer perceptron. The weights of multi-layer perceptron were determined by training the network in self-supervised manner. And the total variation regularization term was used to offer the prior knowledge. We compared our result with some ablation studies, and the results show that out method outperforms existing methods on simulation and experimental data. Under the sparse sampling condition, our method can suppress the artifacts and avoid the ill-posed problem effectively, which reconstruct images with higher signal-to-noise ratio and contrast-to-noise ratio than traditional methods. The high-quality results for sparse data make the proposed method hold the potential for further decreasing the hardware cost of photoacoustic tomography system.