Latents of latents to delineate pixels: hybrid Matryoshka autoencoder-to-U-Net pairing for segmenting large medical images in GPU-poor and low-data regimes

Medical images are often high-resolution and lose important detail if downsampled, making pixel-level methods such as semantic segmentation much less efficient if performed on a low-dimensional image. We propose a low-rank Matryoshka projection and a hybrid segmenting architecture that preserves important information while retaining sufficient pixel geometry for pixel-level tasks. We design the Matryoshka Autoencoder (MatAE-U-Net) which combines the hierarchical encoding of the Matryoshka Autoencoder with the spatial reconstruction capabilities of a U-Net decoder, leveraging multi-scale feature extraction and skip connections to enhance accuracy and generalisation. We apply it to the problem of segmenting the left ventricle (LV) in echocardiographic images using the Stanford EchoNet-D dataset, including 1,000 standardised video-mask pairs of cardiac ultrasound videos resized to 112x112 pixels. The MatAE-UNet model achieves a Mean IoU of 77.68\%, Mean Pixel Accuracy of 97.46\%, and Dice Coefficient of 86.91\%, outperforming the baseline U-Net, which attains a Mean IoU of 74.70\%, Mean Pixel Accuracy of 97.31\%, and Dice Coefficient of 85.20\%. The results highlight the potential of using the U-Net in the recursive Matroshka latent space for imaging problems with low-contrast such as echocardiographic analysis.

The AI Agent Index

Leading AI developers and startups are increasingly deploying agentic AI systems that can plan and execute complex tasks with limited human involvement. However, there is currently no structured framework for documenting the technical components, intended uses, and safety features of agentic systems. To fill this gap, we introduce the AI Agent Index, the first public database to document information about currently deployed agentic AI systems. For each system that meets the criteria for inclusion in the index, we document the system's components (e.g., base model, reasoning implementation, tool use), application domains (e.g., computer use, software engineering), and risk management practices (e.g., evaluation results, guardrails), based on publicly available information and correspondence with developers. We find that while developers generally provide ample information regarding the capabilities and applications of agentic systems, they currently provide limited information regarding safety and risk management practices. The AI Agent Index is available online at https://aiagentindex.mit.edu/

Developing a novel fair-loan-predictor through a multi-sensitive debiasing pipeline: DualFair

Machine learning (ML) models are increasingly used for high-stake applications that can greatly impact people's lives. Despite their use, these models have the potential to be biased towards certain social groups on the basis of race, gender, or ethnicity. Many prior works have attempted to mitigate this "model discrimination" by updating the training data (pre-processing), altering the model learning process (in-processing), or manipulating model output (post-processing). However, these works have not yet been extended to the realm of multi-sensitive parameters and sensitive options (MSPSO), where sensitive parameters are attributes that can be discriminated against (e.g race) and sensitive options are options within sensitive parameters (e.g black or white), thus giving them limited real-world usability. Prior work in fairness has also suffered from an accuracy-fairness tradeoff that prevents both the accuracy and fairness from being high. Moreover, previous literature has failed to provide holistic fairness metrics that work with MSPSO. In this paper, we solve all three of these problems by (a) creating a novel bias mitigation technique called DualFair and (b) developing a new fairness metric (i.e. AWI) that can handle MSPSO. Lastly, we test our novel mitigation method using a comprehensive U.S mortgage lending dataset and show that our classifier, or fair loan predictor, obtains better fairness and accuracy metrics than current state-of-the-art models.