Tackling Cognitive Impairment Detection from Speech: A submission to the PROCESS Challenge

This work describes our group's submission to the PROCESS Challenge 2024, with the goal of assessing cognitive decline through spontaneous speech, using three guided clinical tasks. This joint effort followed a holistic approach, encompassing both knowledge-based acoustic and text-based feature sets, as well as LLM-based macrolinguistic descriptors, pause-based acoustic biomarkers, and multiple neural representations (e.g., LongFormer, ECAPA-TDNN, and Trillson embeddings). Combining these feature sets with different classifiers resulted in a large pool of models, from which we selected those that provided the best balance between train, development, and individual class performance. Our results show that our best performing systems correspond to combinations of models that are complementary to each other, relying on acoustic and textual information from all three clinical tasks.

Unveiling Interpretability in Self-Supervised Speech Representations for Parkinson's Diagnosis

Recent works in pathological speech analysis have increasingly relied on powerful self-supervised speech representations, leading to promising results. However, the complex, black-box nature of these embeddings and the limited research on their interpretability significantly restrict their adoption for clinical diagnosis. To address this gap, we propose a novel, interpretable framework specifically designed to support Parkinson's Disease (PD) diagnosis. Through the design of simple yet effective cross-attention mechanisms for both embedding- and temporal-level analysis, the proposed framework offers interpretability from two distinct but complementary perspectives. Experimental findings across five well-established speech benchmarks for PD detection demonstrate the framework's capability to identify meaningful speech patterns within self-supervised representations for a wide range of assessment tasks. Fine-grained temporal analyses further underscore its potential to enhance the interpretability of deep-learning pathological speech models, paving the way for the development of more transparent, trustworthy, and clinically applicable computer-assisted diagnosis systems in this domain. Moreover, in terms of classification accuracy, our method achieves results competitive with state-of-the-art approaches, while also demonstrating robustness in cross-lingual scenarios when applied to spontaneous speech production.