Glioma Multimodal MRI Analysis System for Tumor Layered Diagnosis via Multi-task Semi-supervised Learning

Gliomas are the most common primary tumors of the central nervous system. Multimodal MRI is widely used for the preliminary screening of gliomas and plays a crucial role in auxiliary diagnosis, therapeutic efficacy, and prognostic evaluation. Currently, the computer-aided diagnostic studies of gliomas using MRI have focused on independent analysis events such as tumor segmentation, grading, and radiogenomic classification, without studying inter-dependencies among these events. In this study, we propose a Glioma Multimodal MRI Analysis System (GMMAS) that utilizes a deep learning network for processing multiple events simultaneously, leveraging their inter-dependencies through an uncertainty-based multi-task learning architecture and synchronously outputting tumor region segmentation, glioma histological subtype, IDH mutation genotype, and 1p/19q chromosome disorder status. Compared with the reported single-task analysis models, GMMAS improves the precision across tumor layered diagnostic tasks. Additionally, we have employed a two-stage semi-supervised learning method, enhancing model performance by fully exploiting both labeled and unlabeled MRI samples. Further, by utilizing an adaptation module based on knowledge self-distillation and contrastive learning for cross-modal feature extraction, GMMAS exhibited robustness in situations of modality absence and revealed the differing significance of each MRI modal. Finally, based on the analysis outputs of the GMMAS, we created a visual and user-friendly platform for doctors and patients, introducing GMMAS-GPT to generate personalized prognosis evaluations and suggestions.

PS6D: Point Cloud Based Symmetry-Aware 6D Object Pose Estimation in Robot Bin-Picking

6D object pose estimation holds essential roles in various fields, particularly in the grasping of industrial workpieces. Given challenges like rust, high reflectivity, and absent textures, this paper introduces a point cloud based pose estimation framework (PS6D). PS6D centers on slender and multi-symmetric objects. It extracts multi-scale features through an attention-guided feature extraction module, designs a symmetry-aware rotation loss and a center distance sensitive translation loss to regress the pose of each point to the centroid of the instance, and then uses a two-stage clustering method to complete instance segmentation and pose estimation. Objects from the Sil\'eane and IPA datasets and typical workpieces from industrial practice are used to generate data and evaluate the algorithm. In comparison to the state-of-the-art approach, PS6D demonstrates an 11.5\% improvement in F$_{1_{inst}}$ and a 14.8\% improvement in Recall. The main part of PS6D has been deployed to the software of Mech-Mind, and achieves a 91.7\% success rate in bin-picking experiments, marking its application in industrial pose estimation tasks.