HypomimiaCoach: An AU-based Digital Therapy System for Hypomimia Detection & Rehabilitation with Parkinson's Disease

Hypomimia is a non-motor symptom of Parkinson's disease that manifests as delayed facial movements and expressions, along with challenges in articulation and emotion. Currently, subjective evaluation by neurologists is the primary method for hypomimia detection, and conventional rehabilitation approaches heavily rely on verbal prompts from rehabilitation physicians. There remains a deficiency in accessible, user-friendly and scientifically rigorous assistive tools for hypomimia treatments. To investigate this, we developed HypomimaCoach, an Action Unit (AU)-based digital therapy system for hypomimia detection and rehabilitation in Parkinson's disease. The HypomimaCoach system was designed to facilitate engagement through the incorporation of both relaxed and controlled rehabilitation exercises, while also stimulating initiative through the integration of digital therapies that incorporated traditional face training methods. We extract action unit(AU) features and their relationship for hypomimia detection. In order to facilitate rehabilitation, a series of training programmes have been devised based on the Action Units (AUs) and patients are provided with real-time feedback through an additional AU recognition model, which guides them through their training routines. A pilot study was conducted with seven participants in China, all of whom exhibited symptoms of Parkinson's disease hypomimia. The results of the pilot study demonstrated a positive impact on participants' self-efficacy, with favourable feedback received. Furthermore, physician evaluations validated the system's applicability in a therapeutic setting for patients with Parkinson's disease, as well as its potential value in clinical applications.

SkinGEN: an Explainable Dermatology Diagnosis-to-Generation Framework with Interactive Vision-Language Models

With the continuous advancement of vision language models (VLMs) technology, remarkable research achievements have emerged in the dermatology field, the fourth most prevalent human disease category. However, despite these advancements, VLM still faces "hallucination" in dermatological diagnosis, and due to the inherent complexity of dermatological conditions, existing tools offer relatively limited support for user comprehension. We propose SkinGEN, a diagnosis-to-generation framework that leverages the stable diffusion (SD) method to generate reference demonstrations from diagnosis results provided by VLM, thereby enhancing the visual explainability for users. Through extensive experiments with Low-Rank Adaptation (LoRA), we identify optimal strategies for skin condition image generation. We conduct a user study with 32 participants evaluating both the system performance and explainability. Results demonstrate that SkinGEN significantly improves users' comprehension of VLM predictions and fosters increased trust in the diagnostic process. This work paves the way for more transparent and user-centric VLM applications in dermatology and beyond.