Counter-intuitive: Large Language Models Can Better Understand Knowledge Graphs Than We Thought

Although the method of enhancing large language models' (LLMs') reasoning ability and reducing their hallucinations through the use of knowledge graphs (KGs) has received widespread attention, the exploration of how to enable LLMs to integrate the structured knowledge in KGs on-the-fly remains inadequate. Researchers often co-train KG embeddings and LLM parameters to equip LLMs with the ability of comprehending KG knowledge. However, this resource-hungry training paradigm significantly increases the model learning cost and is also unsuitable for non-open-source, black-box LLMs. In this paper, we employ complex question answering (CQA) as a task to assess the LLM's ability of comprehending KG knowledge. We conducted a comprehensive comparison of KG knowledge injection methods (from triples to natural language text), aiming to explore the optimal prompting method for supplying KG knowledge to LLMs, thereby enhancing their comprehension of KG. Contrary to our initial expectations, our analysis revealed that LLMs effectively handle messy, noisy, and linearized KG knowledge, outperforming methods that employ well-designed natural language (NL) textual prompts. This counter-intuitive finding provides substantial insights for future research on LLMs' comprehension of structured knowledge.

A Radiomics-Incorporated Deep Ensemble Learning Model for Multi-Parametric MRI-based Glioma Segmentation

We developed a deep ensemble learning model with a radiomics spatial encoding execution for improved glioma segmentation accuracy using multi-parametric MRI (mp-MRI). This model was developed using 369 glioma patients with a 4-modality mp-MRI protocol: T1, contrast-enhanced T1 (T1-Ce), T2, and FLAIR. In each modality volume, a 3D sliding kernel was implemented across the brain to capture image heterogeneity: fifty-six radiomic features were extracted within the kernel, resulting in a 4th order tensor. Each radiomic feature can then be encoded as a 3D image volume, namely a radiomic feature map (RFM). PCA was employed for data dimension reduction and the first 4 PCs were selected. Four deep neural networks as sub-models following the U-Net architecture were trained for the segmenting of a region-of-interest (ROI): each sub-model utilizes the mp-MRI and 1 of the 4 PCs as a 5-channel input for a 2D execution. The 4 softmax probability results given by the U-net ensemble were superimposed and binarized by Otsu method as the segmentation result. Three ensemble models were trained to segment enhancing tumor (ET), tumor core (TC), and whole tumor (WT). The adopted radiomics spatial encoding execution enriches the image heterogeneity information that leads to the successful demonstration of the proposed deep ensemble model, which offers a new tool for mp-MRI based medical image segmentation.