Deep Generative Models-Assisted Automated Labeling for Electron Microscopy Images Segmentation

The rapid advancement of deep learning has facilitated the automated processing of electron microscopy (EM) big data stacks. However, designing a framework that eliminates manual labeling and adapts to domain gaps remains challenging. Current research remains entangled in the dilemma of pursuing complete automation while still requiring simulations or slight manual annotations. Here we demonstrate tandem generative adversarial network (tGAN), a fully label-free and simulation-free pipeline capable of generating EM images for computer vision training. The tGAN can assimilate key features from new data stacks, thus producing a tailored virtual dataset for the training of automated EM analysis tools. Using segmenting nanoparticles for analyzing size distribution of supported catalysts as the demonstration, our findings showcased that the recognition accuracy of tGAN even exceeds the manually-labeling method by 5%. It can also be adaptively deployed to various data domains without further manual manipulation, which is verified by transfer learning from HAADF-STEM to BF-TEM. This generalizability may enable it to extend its application to a broader range of imaging characterizations, liberating microscopists and materials scientists from tedious dataset annotations.

Fast Convergent Federated Learning with Aggregated Gradients

Federated Learning (FL) is a novel machine learning framework, which enables multiple distributed devices cooperatively to train a shared model scheduled by a central server while protecting private data locally. However, the non-independent-and-identically-distributed (Non-IID) data samples and frequent communication across participants may significantly slow down the convergent rate and increase communication costs. To achieve fast convergence, we ameliorate the conventional local updating rule by introducing the aggregated gradients at each local update epoch, and propose an adaptive learning rate algorithm that further takes the deviation of local parameter and global parameter into consideration. The above adaptive learning rate design requires all clients' local information including the local parameters and gradients, which is challenging as there is no communication during the local update epochs. To obtain a decentralized adaptive learning rate for each client, we utilize the mean field approach by introducing two mean field terms to estimate the average local parameters and gradients respectively, which does not require the clients to exchange their local information with each other at each local epoch. Numerical results show that our proposed framework is superior to the state-of-art FL schemes in both model accuracy and convergent rate for IID and Non-IID datasets.