AuD-Former: A Hierarchical Transformer Network for Multimodal Audio-Based Disease Prediction

Audio-based disease prediction is emerging as a promising supplement to traditional medical diagnosis methods, facilitating early, convenient, and non-invasive disease detection and prevention. Multimodal fusion, which integrates features from various domains within or across bio-acoustic modalities, has proven effective in enhancing diagnostic performance. However, most existing methods in the field employ unilateral fusion strategies that focus solely on either intra-modal or inter-modal fusion. This approach limits the full exploitation of the complementary nature of diverse acoustic feature domains and bio-acoustic modalities. Additionally, the inadequate and isolated exploration of latent dependencies within modality-specific and modality-shared spaces curtails their capacity to manage the inherent heterogeneity in multimodal data. To fill these gaps, we propose AuD-Former, a hierarchical transformer network designed for general multimodal audio-based disease prediction. Specifically, we seamlessly integrate intra-modal and inter-modal fusion in a hierarchical manner and proficiently encode the necessary intra-modal and inter-modal complementary correlations, respectively. Comprehensive experiments demonstrate that AuD-Former achieves state-of-the-art performance in predicting three diseases: COVID-19, Parkinson's disease, and pathological dysarthria, showcasing its promising potential in a broad context of audio-based disease prediction tasks. Additionally, extensive ablation studies and qualitative analyses highlight the significant benefits of each main component within our model.

Mitigating Sex Bias in Audio Data-driven COPD and COVID-19 Breathing Pattern Detection Models

In the healthcare industry, researchers have been developing machine learning models to automate diagnosing patients with respiratory illnesses based on their breathing patterns. However, these models do not consider the demographic biases, particularly sex bias, that often occur when models are trained with a skewed patient dataset. Hence, it is essential in such an important industry to reduce this bias so that models can make fair diagnoses. In this work, we examine the bias in models used to detect breathing patterns of two major respiratory diseases, i.e., chronic obstructive pulmonary disease (COPD) and COVID-19. Using decision tree models trained with audio recordings of breathing patterns obtained from two open-source datasets consisting of 29 COPD and 680 COVID-19-positive patients, we analyze the effect of sex bias on the models. With a threshold optimizer and two constraints (demographic parity and equalized odds) to mitigate the bias, we witness 81.43% (demographic parity difference) and 71.81% (equalized odds difference) improvements. These findings are statistically significant.

Toward Mitigating Sex Bias in Pilot Trainees' Stress and Fatigue Modeling

While researchers have been trying to understand the stress and fatigue among pilots, especially pilot trainees, and to develop stress/fatigue models to automate the process of detecting stress/fatigue, they often do not consider biases such as sex in those models. However, in a critical profession like aviation, where the demographic distribution is disproportionately skewed to one sex, it is urgent to mitigate biases for fair and safe model predictions. In this work, we investigate the perceived stress/fatigue of 69 college students, including 40 pilot trainees with around 63% male. We construct models with decision trees first without bias mitigation and then with bias mitigation using a threshold optimizer with demographic parity and equalized odds constraints 30 times with random instances. Using bias mitigation, we achieve improvements of 88.31% (demographic parity difference) and 54.26% (equalized odds difference), which are also found to be statistically significant.

Transfer Learning to Detect COVID-19 Coughs with Incremental Addition of Patient Coughs to Healthy People's Cough Detection Models

Millions of people have died worldwide from COVID-19. In addition to its high death toll, COVID-19 has led to unbearable suffering for individuals and a huge global burden to the healthcare sector. Therefore, researchers have been trying to develop tools to detect symptoms of this human-transmissible disease remotely to control its rapid spread. Coughing is one of the common symptoms that researchers have been trying to detect objectively from smartphone microphone-sensing. While most of the approaches to detect and track cough symptoms rely on machine learning models developed from a large amount of patient data, this is not possible at the early stage of an outbreak. In this work, we present an incremental transfer learning approach that leverages the relationship between healthy peoples' coughs and COVID-19 patients' coughs to detect COVID-19 coughs with reasonable accuracy using a pre-trained healthy cough detection model and a relatively small set of patient coughs, reducing the need for large patient dataset to train the model. This type of model can be a game changer in detecting the onset of a novel respiratory virus.

Discovering COVID-19 Coughing and Breathing Patterns from Unlabeled Data Using Contrastive Learning with Varying Pre-Training Domains

Rapid discovery of new diseases, such as COVID-19 can enable a timely epidemic response, preventing the large-scale spread and protecting public health. However, limited research efforts have been taken on this problem. In this paper, we propose a contrastive learning-based modeling approach for COVID-19 coughing and breathing pattern discovery from non-COVID coughs. To validate our models, extensive experiments have been conducted using four large audio datasets and one image dataset. We further explore the effects of different factors, such as domain relevance and augmentation order on the pre-trained models. Our results show that the proposed model can effectively distinguish COVID-19 coughing and breathing from unlabeled data and labeled non-COVID coughs with an accuracy of up to 0.81 and 0.86, respectively. Findings from this work will guide future research to detect an outbreak of a new disease early.

Predicting dominant hand from spatiotemporal context varying physiological data

Health metrics from wrist-worn devices demand an automatic dominant hand prediction to keep an accurate operation. The prediction would improve reliability, enhance the consumer experience, and encourage further development of healthcare applications. This paper aims to evaluate the use of physiological and spatiotemporal context information from a two-hand experiment to predict the wrist placement of a commercial smartwatch. The main contribution is a methodology to obtain an effective model and features from low sample rate physiological sensors and a self-reported context survey. Results show an effective dominant hand prediction using data from a single subject under real-life conditions.

Automatic Anomalies Detection in Hydraulic Devices

Nowadays, the applications of hydraulic systems are present in a wide variety of devices in both industrial and everyday environments. The implementation and usage of hydraulic systems have been well documented; however, today, this still faces a challenge, the integration of tools that allow more accurate information about the functioning and operation of these systems for proactive decision-making. In industrial applications, many sensors and methods exist to measure and determine the status of process variables (e.g., flow, pressure, force). Nevertheless, little has been done to have systems that can provide users with device-health information related to hydraulic devices integrated into the machinery. Implementing artificial intelligence (AI) technologies and machine learning (ML) models in hydraulic system components has been identified as a solution to the challenge many industries currently face: optimizing processes and carrying them out more safely and efficiently. This paper presents a solution for the characterization and estimation of anomalies in one of the most versatile and used devices in hydraulic systems, cylinders. AI and ML models were implemented to determine the current operating status of these hydraulic components and whether they are working correctly or if a failure mode or abnormal condition is present.

Opportunistic Multi-Modal User Authentication for Health-Tracking IoT Wearables

With the advancement of technologies, market wearables are becoming increasingly popular with a range of services, including providing access to bank accounts, accessing cars, monitoring patients remotely, among several others. However, often these wearables collect various sensitive personal information of a user with no to limited authentication, e.g., knowledge-based external authentication techniques, such as PINs. While most of these external authentication techniques suffer from multiple limitations, including recall burden, human errors, or biases, researchers have started using various physiological and behavioral data, such as gait and heart rate, collected by the wearables to authenticate a wearable user implicitly with a limited accuracy due to sensing and computing constraints of wearables. In this work, we explore the usefulness of blood oxygen saturation SpO2 values collected from the Oximeter device to distinguish a user from others. From a cohort of 25 subjects, we find that 92% of the cases SpO2 can distinguish pairs of users. From detailed modeling and performance analysis, we observe that while SpO2 alone can obtain an average accuracy of 0.69 and F1 score of 0.69, the addition of heart rate (HR) can improve the average identification accuracy by 15% and F1 score by 13%. These results show promise in using SpO2 along with other biometrics to develop implicit continuous authentications for wearables.

Context-Dependent Implicit Authentication for Wearable Device User

As market wearables are becoming popular with a range of services, including making financial transactions, accessing cars, etc. that they provide based on various private information of a user, security of this information is becoming very important. However, users are often flooded with PINs and passwords in this internet of things (IoT) world. Additionally, hard-biometric, such as facial or finger recognition, based authentications are not adaptable for market wearables due to their limited sensing and computation capabilities. Therefore, it is a time demand to develop a burden-free implicit authentication mechanism for wearables using the less-informative soft-biometric data that are easily obtainable from the market wearables. In this work, we present a context-dependent soft-biometric-based wearable authentication system utilizing the heart rate, gait, and breathing audio signals. From our detailed analysis, we find that a binary support vector machine (SVM) with radial basis function (RBF) kernel can achieve an average accuracy of $0.94 \pm 0.07$, $F_1$ score of $0.93 \pm 0.08$, an equal error rate (EER) of about $0.06$ at a lower confidence threshold of 0.52, which shows the promise of this work.

Continuous Authentication of Wearable Device Users from Heart Rate, Gait, and Breathing Data

The security of private information is becoming the bedrock of an increasingly digitized society. While the users are flooded with passwords and PINs, these gold-standard explicit authentications are becoming less popular and valuable. Recent biometric-based authentication methods, such as facial or finger recognition, are getting popular due to their higher accuracy. However, these hard-biometric-based systems require dedicated devices with powerful sensors and authentication models, which are often limited to most of the market wearables. Still, market wearables are collecting various private information of a user and are becoming an integral part of life: accessing cars, bank accounts, etc. Therefore, time demands a burden-free implicit authentication mechanism for wearables using the less-informative soft-biometric data that are easily obtainable from modern market wearables. In this work, we present a context-dependent soft-biometric-based authentication system for wearables devices using heart rate, gait, and breathing audio signals. From our detailed analysis using the "leave-one-out" validation, we find that a lighter $k$-Nearest Neighbor ($k$-NN) model with $k = 2$ can obtain an average accuracy of $0.93 \pm 0.06$, $F_1$ score $0.93 \pm 0.03$, and {\em false positive rate} (FPR) below $0.08$ at 50\% level of confidence, which shows the promise of this work.