Health metrics from wrist-worn devices demand an automatic dominant hand prediction to keep an accurate operation. The prediction would improve reliability, enhance the consumer experience, and encourage further development of healthcare applications. This paper aims to evaluate the use of physiological and spatiotemporal context information from a two-hand experiment to predict the wrist placement of a commercial smartwatch. The main contribution is a methodology to obtain an effective model and features from low sample rate physiological sensors and a self-reported context survey. Results show an effective dominant hand prediction using data from a single subject under real-life conditions.