AI in radiological imaging of soft-tissue and bone tumours: a systematic review evaluating against CLAIM and FUTURE-AI guidelines

Soft-tissue and bone tumours (STBT) are rare, diagnostically challenging lesions with variable clinical behaviours and treatment approaches. This systematic review provides an overview of Artificial Intelligence (AI) methods using radiological imaging for diagnosis and prognosis of these tumours, highlighting challenges in clinical translation, and evaluating study alignment with the Checklist for AI in Medical Imaging (CLAIM) and the FUTURE-AI international consensus guidelines for trustworthy and deployable AI to promote the clinical translation of AI methods. The review covered literature from several bibliographic databases, including papers published before 17/07/2024. Original research in peer-reviewed journals focused on radiology-based AI for diagnosing or prognosing primary STBT was included. Exclusion criteria were animal, cadaveric, or laboratory studies, and non-English papers. Abstracts were screened by two of three independent reviewers for eligibility. Eligible papers were assessed against guidelines by one of three independent reviewers. The search identified 15,015 abstracts, from which 325 articles were included for evaluation. Most studies performed moderately on CLAIM, averaging a score of 28.9$\pm$7.5 out of 53, but poorly on FUTURE-AI, averaging 5.1$\pm$2.1 out of 30. Imaging-AI tools for STBT remain at the proof-of-concept stage, indicating significant room for improvement. Future efforts by AI developers should focus on design (e.g. define unmet clinical need, intended clinical setting and how AI would be integrated in clinical workflow), development (e.g. build on previous work, explainability), evaluation (e.g. evaluating and addressing biases, evaluating AI against best practices), and data reproducibility and availability (making documented code and data publicly available). Following these recommendations could improve clinical translation of AI methods.

Audio-Visual Floorplan Reconstruction

Given only a few glimpses of an environment, how much can we infer about its entire floorplan? Existing methods can map only what is visible or immediately apparent from context, and thus require substantial movements through a space to fully map it. We explore how both audio and visual sensing together can provide rapid floorplan reconstruction from limited viewpoints. Audio not only helps sense geometry outside the camera's field of view, but it also reveals the existence of distant freespace (e.g., a dog barking in another room) and suggests the presence of rooms not visible to the camera (e.g., a dishwasher humming in what must be the kitchen to the left). We introduce AV-Map, a novel multi-modal encoder-decoder framework that reasons jointly about audio and vision to reconstruct a floorplan from a short input video sequence. We train our model to predict both the interior structure of the environment and the associated rooms' semantic labels. Our results on 85 large real-world environments show the impact: with just a few glimpses spanning 26% of an area, we can estimate the whole area with 66% accuracy -- substantially better than the state of the art approach for extrapolating visual maps.

Audio-Visual Embodied Navigation

Moving around in the world is naturally a multisensory experience, but today's embodied agents are deaf - restricted to solely their visual perception of the environment. We introduce audio-visual navigation for complex, acoustically and visually realistic 3D environments. By both seeing and hearing, the agent must learn to navigate to an audio-based target. We develop a multi-modal deep reinforcement learning pipeline to train navigation policies end-to-end from a stream of egocentric audio-visual observations, allowing the agent to (1) discover elements of the geometry of the physical space indicated by the reverberating audio and (2) detect and follow sound-emitting targets. We further introduce audio renderings based on geometrical acoustic simulations for a set of publicly available 3D assets and instrument AI-Habitat to support the new sensor, making it possible to insert arbitrary sound sources in an array of apartment, office, and hotel environments. Our results show that audio greatly benefits embodied visual navigation in 3D spaces.