Abstract:Three-dimensional (3D) freehand ultrasound (US) is a widely used imaging modality that allows non-invasive imaging of medical anatomy without radiation exposure. The freehand 3D US surface reconstruction is vital to acquire the accurate anatomical structures needed for modeling, registration, and visualization. However, the currently used traditional methods cannot produce a high-quality surface due to imaging noise and connectivity issues in US. Although the deep learning-based approaches exhibiting the improvements in smoothness, continuity and resolution, the investigation into freehand 3D US remains limited. In this study, we introduce a self-supervised neural implicit surface reconstruction method to learn the signed distance functions (SDFs) from freehand 3D US volumetric point clouds. In particular, our method iteratively learns the SDFs by moving the 3D queries sampled around the point clouds to approximate the surface with the assistance of two novel geometric constraints. We assess our method on the three imaging systems, using twenty-three shapes that include six distinct anthropomorphic phantoms datasets and seventeen in vivo carotid artery datasets. Experimental results on phantoms outperform the existing approach, with a 67% reduction in Chamfer distance, 60% in Hausdorff distance, and 61% in Average absolute distance. Furthermore, our method achieves a 0.92 Dice score on the in vivo datasets and demonstrates great clinical potential.