Abstract:Accurate atmospheric wind field information is crucial for various applications, including weather forecasting, aviation safety, and disaster risk reduction. However, obtaining high spatiotemporal resolution wind data remains challenging due to limitations in traditional in-situ observations and remote sensing techniques, as well as the computational expense and biases of numerical weather prediction (NWP) models. This paper introduces G-WindCast, a novel deep learning framework that leverages signal strength variations from 5G Global Navigation Satellite System (GNSS) signals to retrieve and forecast three-dimensional (3D) atmospheric wind fields. The framework utilizes Forward Neural Networks (FNN) and Transformer networks to capture complex, nonlinear, and spatiotemporal relationships between GNSS-derived features and wind dynamics. Our preliminary results demonstrate promising accuracy in both wind retrieval and short-term wind forecasting (up to 30 minutes lead time), with skill scores comparable to high-resolution NWP outputs in certain scenarios. The model exhibits robustness across different forecast horizons and pressure levels, and its predictions for wind speed and direction show superior agreement with observations compared to concurrent ERA5 reanalysis data. Furthermore, we show that the system can maintain excellent performance for localized forecasting even with a significantly reduced number of GNSS stations (e.g., around 100), highlighting its cost-effectiveness and scalability. This interdisciplinary approach underscores the transformative potential of exploiting non-traditional data sources and deep learning for advanced environmental monitoring and real-time atmospheric applications.
Abstract:The distinct characteristics of multiomics data, including complex interactions within and across biological layers and disease heterogeneity (e.g., heterogeneity in etiology and clinical symptoms), drive us to develop novel designs to address unique challenges in multiomics prediction. In this paper, we propose the multi-view knowledge transfer learning (MVKTrans) framework, which transfers intra- and inter-omics knowledge in an adaptive manner by reviewing data heterogeneity and suppressing bias transfer, thereby enhancing classification performance. Specifically, we design a graph contrastive module that is trained on unlabeled data to effectively learn and transfer the underlying intra-omics patterns to the supervised task. This unsupervised pretraining promotes learning general and unbiased representations for each modality, regardless of the downstream tasks. In light of the varying discriminative capacities of modalities across different diseases and/or samples, we introduce an adaptive and bi-directional cross-omics distillation module. This module automatically identifies richer modalities and facilitates dynamic knowledge transfer from more informative to less informative omics, thereby enabling a more robust and generalized integration. Extensive experiments on four real biomedical datasets demonstrate the superior performance and robustness of MVKTrans compared to the state-of-the-art. Code and data are available at https://github.com/Yaolab-fantastic/MVKTrans.
Abstract:Molecular property prediction has gained significant attention due to its transformative potential in multiple scientific disciplines. Conventionally, a molecule graph can be represented either as a graph-structured data or a SMILES text. Recently, the rapid development of Large Language Models (LLMs) has revolutionized the field of NLP. Although it is natural to utilize LLMs to assist in understanding molecules represented by SMILES, the exploration of how LLMs will impact molecular property prediction is still in its early stage. In this work, we advance towards this objective through two perspectives: zero/few-shot molecular classification, and using the new explanations generated by LLMs as representations of molecules. To be specific, we first prompt LLMs to do in-context molecular classification and evaluate their performance. After that, we employ LLMs to generate semantically enriched explanations for the original SMILES and then leverage that to fine-tune a small-scale LM model for multiple downstream tasks. The experimental results highlight the superiority of text explanations as molecular representations across multiple benchmark datasets, and confirm the immense potential of LLMs in molecular property prediction tasks. Codes are available at \url{https://github.com/ChnQ/LLM4Mol}.