Synthetic Time Series Data Generation for Healthcare Applications: A PCG Case Study

The generation of high-quality medical time series data is essential for advancing healthcare diagnostics and safeguarding patient privacy. Specifically, synthesizing realistic phonocardiogram (PCG) signals offers significant potential as a cost-effective and efficient tool for cardiac disease pre-screening. Despite its potential, the synthesis of PCG signals for this specific application received limited attention in research. In this study, we employ and compare three state-of-the-art generative models from different categories - WaveNet, DoppelGANger, and DiffWave - to generate high-quality PCG data. We use data from the George B. Moody PhysioNet Challenge 2022. Our methods are evaluated using various metrics widely used in the previous literature in the domain of time series data generation, such as mean absolute error and maximum mean discrepancy. Our results demonstrate that the generated PCG data closely resembles the original datasets, indicating the effectiveness of our generative models in producing realistic synthetic PCG data. In our future work, we plan to incorporate this method into a data augmentation pipeline to synthesize abnormal PCG signals with heart murmurs, in order to address the current scarcity of abnormal data. We hope to improve the robustness and accuracy of diagnostic tools in cardiology, enhancing their effectiveness in detecting heart murmurs.

Automating Quantum Software Maintenance: Flakiness Detection and Root Cause Analysis

Flaky tests, which pass or fail inconsistently without code changes, are a major challenge in software engineering in general and in quantum software engineering in particular due to their complexity and probabilistic nature, leading to hidden issues and wasted developer effort. We aim to create an automated framework to detect flaky tests in quantum software and an extended dataset of quantum flaky tests, overcoming the limitations of manual methods. Building on prior manual analysis of 14 quantum software repositories, we expanded the dataset and automated flaky test detection using transformers and cosine similarity. We conducted experiments with Large Language Models (LLMs) from the OpenAI GPT and Meta LLaMA families to assess their ability to detect and classify flaky tests from code and issue descriptions. Embedding transformers proved effective: we identified 25 new flaky tests, expanding the dataset by 54%. Top LLMs achieved an F1-score of 0.8871 for flakiness detection but only 0.5839 for root cause identification. We introduced an automated flaky test detection framework using machine learning, showing promising results but highlighting the need for improved root cause detection and classification in large quantum codebases. Future work will focus on improving detection techniques and developing automatic flaky test fixes.