Offline reinforcement learning (RL) aims to learn policies from static datasets of previously collected trajectories. Existing methods for offline RL either constrain the learned policy to the support of offline data or utilize model-based virtual environments to generate simulated rollouts. However, these methods suffer from (i) poor generalization to unseen states; and (ii) trivial improvement from low-qualified rollout simulation. In this paper, we propose offline trajectory generalization through world transformers for offline reinforcement learning (OTTO). Specifically, we use casual Transformers, a.k.a. World Transformers, to predict state dynamics and the immediate reward. Then we propose four strategies to use World Transformers to generate high-rewarded trajectory simulation by perturbing the offline data. Finally, we jointly use offline data with simulated data to train an offline RL algorithm. OTTO serves as a plug-in module and can be integrated with existing offline RL methods to enhance them with better generalization capability of transformers and high-rewarded data augmentation. Conducting extensive experiments on D4RL benchmark datasets, we verify that OTTO significantly outperforms state-of-the-art offline RL methods.