Arbitrary Reduction of MRI Slice Spacing Based on Local-Aware Implicit Representation

Magnetic resonance (MR) images are often acquired in 2D settings for real clinical applications. The 3D volumes reconstructed by stacking multiple 2D slices have large inter-slice spacing, resulting in lower inter-slice resolution than intra-slice resolution. Super-resolution is a powerful tool to reduce the inter-slice spacing of 3D images to facilitate subsequent visualization and computation tasks. However, most existing works train the super-resolution network at a fixed ratio, which is inconvenient in clinical scenes due to the heterogeneous parameters in MR scanning. In this paper, we propose a single super-resolution network to reduce the inter-slice spacing of MR images at an arbitrarily adjustable ratio. Specifically, we view the input image as a continuous implicit function of coordinates. The intermediate slices of different spacing ratios could be constructed according to the implicit representation up-sampled in the continuous domain. We particularly propose a novel local-aware spatial attention mechanism and long-range residual learning to boost the quality of the output image. The experimental results demonstrate the superiority of our proposed method, even compared to the models trained at a fixed ratio.