Abstract:Magnetic Resonance Imaging (MRI) is a multi-contrast imaging technique in which different contrast images share similar structural information. However, conventional diffusion models struggle to effectively leverage this structural similarity. Recently, the Schr\"odinger Bridge (SB), a nonlinear extension of the diffusion model, has been proposed to establish diffusion paths between any distributions, allowing the incorporation of guided priors. This study proposes an SB-based, multi-contrast image-guided reconstruction framework that establishes a diffusion bridge between the guiding and target image distributions. By using the guiding image along with data consistency during sampling, the target image is reconstructed more accurately. To better address structural differences between images, we introduce an inversion strategy from the field of image editing, termed $\mathbf{I}^2$SB-inversion. Experiments on a paried T1 and T2-FLAIR datasets demonstrate that $\mathbf{I}^2$SB-inversion achieve a high acceleration up to 14.4 and outperforms existing methods in terms of both reconstruction accuracy and stability.