Abstract:We consider the problem of learning the exact skeleton of general discrete Bayesian networks from potentially corrupted data. Building on distributionally robust optimization and a regression approach, we propose to optimize the most adverse risk over a family of distributions within bounded Wasserstein distance or KL divergence to the empirical distribution. The worst-case risk accounts for the effect of outliers. The proposed approach applies for general categorical random variables without assuming faithfulness, an ordinal relationship or a specific form of conditional distribution. We present efficient algorithms and show the proposed methods are closely related to the standard regularized regression approach. Under mild assumptions, we derive non-asymptotic guarantees for successful structure learning with logarithmic sample complexities for bounded-degree graphs. Numerical study on synthetic and real datasets validates the effectiveness of our method. Code is available at https://github.com/DanielLeee/drslbn.
Abstract:Whole brain segmentation is an important neuroimaging task that segments the whole brain volume into anatomically labeled regions-of-interest. Convolutional neural networks have demonstrated good performance in this task. Existing solutions, usually segment the brain image by classifying the voxels, or labeling the slices or the sub-volumes separately. Their representation learning is based on parts of the whole volume whereas their labeling result is produced by aggregation of partial segmentation. Learning and inference with incomplete information could lead to sub-optimal final segmentation result. To address these issues, we propose to adopt a full volume framework, which feeds the full volume brain image into the segmentation network and directly outputs the segmentation result for the whole brain volume. The framework makes use of complete information in each volume and can be implemented easily. An effective instance in this framework is given subsequently. We adopt the $3$D high-resolution network (HRNet) for learning spatially fine-grained representations and the mixed precision training scheme for memory-efficient training. Extensive experiment results on a publicly available $3$D MRI brain dataset show that our proposed model advances the state-of-the-art methods in terms of segmentation performance. Source code is publicly available at https://github.com/microsoft/VoxHRNet.